500P227100
CD22 (soluble) Polyclonal Antibody, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 500P227100-Each-of-1 | In Stock | ₹ 24,812.40 |
500P227100 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,812.40
GST (18%): ₹ 4,466.232
Total Price: ₹ 29,278.632
Antigen
CD22 (soluble)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD22
Gene Alias
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
933
Content And Storage
-20°C
Applications
ELISA, Western Blot
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P20273
Gene Symbols
CD22
Immunogen
CHO cells-derived Recombinant Human sCD22
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Lyophilized
Related Products
Description
- AA Seq
- of rec
- protein: SKWVFEHPET LYAWEGACVW IPCTYRALDG DLESFILFHN PEYNKNTSKF DGTRLYESTK DGKVPSEQKR VQFLGDKNKN CTLSIHPVHL NDSGQLGLRM ESKTEKWMER IHLNVSERPF PPHIQLPPEI QESQEVTLTC LLNFSCYGYP IQLQWLLEGV PMRQAAVTST SLTIKSVFTR SELKFSPQWS HHGKIVTCQL QDADGKFLSN DTVQLNVKHT PKLEIKVTPS DAIVREGDSV TMTCEVSSSN PEYTTVSWLK DGTSLKKQNT FTLNLREVTK DQSGKYCCQV SNDVGPGRSE EVFLQVQYAP EPSTVQILHS PAVEGSQVEF LCMSLANPLP TNYTWYHNGK EMQGRTEEKV HIPKILPWHA GTYSCVAENI LGTGQRGPGA ELDVQYPPKK VTTVIQNPMP IREGDTVTLS CNYNSSNPSV TRYEWKPHGA WEEPSLGVLK IQNVGWDNTT IACARCNSWC SWASPVALNV QYAPRDVRVR KIKPLSEIHS GNSVSLQCDF SSSHPKEVQF FWEKNGRLLG KESQLNFDSI SPEDAGSYSC WVNNSIGQTA SKAWTLEVLY APRRLRVSMS PGDQVMEGKS ATLTCESDAN PPVSHYTWFD WNNQSLPHHS QKLRLEPVKV QHSGAYWCQG TNSVGKGRSP LSTLTVYYSP ETIGRR
- Sandwich ELISA: To detect Hu sCD22 by sandwich ELISA (using 100 uL/well antibody solution) a conc
- of 0.5-2.0 ug/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Hu sCD22 (500-P227Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of rec
- Hu sCD22
- WB: To detect Hu sCD22 by WB analysis this antibody can be used at a conc
- of 0.1-0.2 ug/mL
- Used in conjunction with compatible secondary reagents the detection limit for rec
- Hu sCD22 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
- CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
- CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
- Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
- CD22 is also strongly expressed in hairy cell leukemia
- CD22 preferentially binds to alpha2,6-linked sialic acid
- The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
- Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
- CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
- CD22 is also strongly expressed in hairy cell leukemia
- CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.
Compare Similar Items
Show Difference
Antigen: CD22 (soluble)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD22
Gene Alias: A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 933
Content And Storage: -20°C
Applications: ELISA, Western Blot
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P20273
Gene Symbols: CD22
Immunogen: CHO cells-derived Recombinant Human sCD22
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
CD22 (soluble)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD22
Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
933
Content And Storage:
-20°C
Applications:
ELISA, Western Blot
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P20273
Gene Symbols:
CD22
Immunogen:
CHO cells-derived Recombinant Human sCD22
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: CD22 (soluble)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD22
Gene Alias: A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 933
Content And Storage: -20°C
Applications: ELISA, Western Blot
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P20273
Gene Symbols: CD22
Immunogen: CHO cells-derived Recombinant Human sCD22
Quantity: 1 mg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
CD22 (soluble)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD22
Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
933
Content And Storage:
-20°C
Applications:
ELISA, Western Blot
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P20273
Gene Symbols:
CD22
Immunogen:
CHO cells-derived Recombinant Human sCD22
Quantity:
1 mg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: CD22 (soluble)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD22
Gene Alias: A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 933
Content And Storage: -20°C
Applications: ELISA, Western Blot
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P20273
Gene Symbols: CD22
Immunogen: CHO cells-derived Recombinant Human sCD22
Quantity: 50μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
CD22 (soluble)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD22
Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
933
Content And Storage:
-20°C
Applications:
ELISA, Western Blot
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P20273
Gene Symbols:
CD22
Immunogen:
CHO cells-derived Recombinant Human sCD22
Quantity:
50μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: IGFBP-1
Classification: Polyclonal
Conjugate: Biotin
Gene: IGFBP1
Gene Alias: AFBP; alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; hIGFBP-1; IBP 1; IBP1; IBP-1; IGF BP25; IGFBA; IGF-binding protein 1; IGFBP; IGFBP 1; Igfbp1; Igfbp-1; IGF-BP25; Insulin like growth factor binding protein; insulin like growth factor binding protein 1; insulin-like growth factor binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3484
Content And Storage: -20°C
Applications: ELISA, Western Blot
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P08833
Gene Symbols: IGFBP1
Immunogen: E.coli-derived Recombinant Human IGF-BP1
Quantity: 2 x 500 μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
IGFBP-1
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
IGFBP1
Gene Alias:
AFBP; alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; hIGFBP-1; IBP 1; IBP1; IBP-1; IGF BP25; IGFBA; IGF-binding protein 1; IGFBP; IGFBP 1; Igfbp1; Igfbp-1; IGF-BP25; Insulin like growth factor binding protein; insulin like growth factor binding protein 1; insulin-like growth factor binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3484
Content And Storage:
-20°C
Applications:
ELISA, Western Blot
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P08833
Gene Symbols:
IGFBP1
Immunogen:
E.coli-derived Recombinant Human IGF-BP1
Quantity:
2 x 500 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized