500P63BT1MG

RANKL (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 500P63BT1MG-Each-of-1 In Stock ₹ 3,37,534.20

500P63BT1MG - Each of 1

₹ 3,37,534.20

In Stock

Quantity

1

Base Price: ₹ 3,37,534.20

GST (18%): ₹ 60,756.156

Total Price: ₹ 3,98,290.356

Antigen

RANKL (soluble)

Classification

Polyclonal

Conjugate

Biotin

Gene

TNFSF11

Gene Alias

CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21943

Content And Storage

-20°C

Applications

ELISA, Western Blot

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

O35235

Gene Symbols

TNFSF11

Immunogen

E.coli-derived, 19.4 kDa Recombinant Murine sRANK Ligand

Quantity

2 x 500μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: PAMMEGSWLD VAQRGKPEAQ PFAHLTINAA SIPSGSHKVT LSSWYHDRGW AKISNMTLSN GKLRVNQDGF YYLYANICFR HHETSGSVPT DYLQLMVYVV KTSIKIPSSH NLMKGGSTKN WSGNSEFHFY SINVGGFFKL RAGEEISIQV SNPSLLDPDQ DATYFGAFKV QDID
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine sRANK Ligand
  • Anti-Murine sRANK Ligand-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect msRANKL by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine sRANKL (500-P63) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant msRANKL
  • Western Blot: To detect msRANKL by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 mg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant msRANKL is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P63BT-1MG will be provided as 2 x 500 μg This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
  • This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
  • T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
  • This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
  • Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
  • The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
  • Two alternatively spliced transcript variants have been found.

Compare Similar Items

Show Difference

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Fischer Scientific

500P63BT1MG

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Antigen:
RANKL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21943

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O35235

Gene Symbols:
TNFSF11

Immunogen:
E.coli-derived, 19.4 kDa Recombinant Murine sRANK Ligand

Quantity:
2 x 500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

Img

Fischer Scientific

500P63BT25

--


Antigen:
RANKL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21943

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O35235

Gene Symbols:
TNFSF11

Immunogen:
E.coli-derived, 19.4 kDa Recombinant Murine sRANK Ligand

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

Img

Fischer Scientific

500P63BT50

--


Antigen:
RANKL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21943

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O35235

Gene Symbols:
TNFSF11

Immunogen:
E.coli-derived, 19.4 kDa Recombinant Murine sRANK Ligand

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

Img

Fischer Scientific

500P64100UG

--


Antigen:
TNF alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tnf

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21926

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P06804

Gene Symbols:
Tnf

Immunogen:
E.coli-derived Recombinant Murine TNF-alpha

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized