53-598-282
CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-598-282-Each-of-1 | In Stock | ₹ 32,940.60 |
53-598-282 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,940.60
GST (18%): ₹ 5,929.308
Total Price: ₹ 38,869.908
Antigen
CD274 (PD-L1, B7-H1)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9EP73
Gene Symbols
Cd274
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
60533
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
MIH5
Conjugate
Alexa Fluor 488
Gene
Cd274
Gene Alias
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a λ
Related Products
Description
- Description: The MIH5 monoclonal antibody reacts with mouse B7-H1, also known as PD-L1
- B7-H1, a member of the B7 family, has a predicted molecular weight of approximately 40 kDa and belongs to the Ig superfamily
- B7-H1 is expressed on a majority of leukocytes including T, B, NK and DC
- B7-H1 is a ligand for PD-1
- Interaction of PD-1 with either PD-L1 (B7-H1) or PD-L2 (B7-DC) results in inhibition of T and B cell responses
- MIH5 is reported to be a blocking antibody
- Applications Reported: This MIH5 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This MIH5 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member
- To date, one specific receptor has been identified that can be ligated by PD-L1
- This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling
- Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production
- PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation
- Thus, PD-L1 might play an important role in tumor immune evasion.
Compare Similar Items
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Antigen: CD274 (PD-L1, B7-H1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EP73
Gene Symbols: Cd274
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 60533
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: MIH5
Conjugate: Alexa Fluor 488
Gene: Cd274
Gene Alias: A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a λ
Antigen:
CD274 (PD-L1, B7-H1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EP73
Gene Symbols:
Cd274
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
60533
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MIH5
Conjugate:
Alexa Fluor 488
Gene:
Cd274
Gene Alias:
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a λ
Antigen: CD274 (PD-L1, B7-H1)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: Q9NZQ7
Gene Symbols: Cd274
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29126
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: MIH1
Conjugate: Alexa Fluor 488
Gene: Cd274
Gene Alias: A530045L16Rik, B7 homolog 1, B7-H, B7h1, B7-H1, Cd274, CD274 antigen, CD274 molecule, PDCD1 ligand 1, Pdcd1l1, Pdcd1lg1, Pdl1, PD-L1, pdl-1, Programmed cell death 1 ligand 1, programmed death ligand 1, RGD1566211, sCD274, soluble CD274, soluble PD L1, sPD L1
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD274 (PD-L1, B7-H1)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q9NZQ7
Gene Symbols:
Cd274
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29126
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MIH1
Conjugate:
Alexa Fluor 488
Gene:
Cd274
Gene Alias:
A530045L16Rik, B7 homolog 1, B7-H, B7h1, B7-H1, Cd274, CD274 antigen, CD274 molecule, PDCD1 ligand 1, Pdcd1l1, Pdcd1lg1, Pdl1, PD-L1, pdl-1, Programmed cell death 1 ligand 1, programmed death ligand 1, RGD1566211, sCD274, soluble CD274, soluble PD L1, sPD L1
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: DDX5
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P17844
Gene Symbols: DDX5
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1655
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry
Clone: Ab204
Conjugate: Alexa Fluor 488
Gene: DDX5
Gene Alias: 2600009A06Rik, ATP-dependent RNA helicase DDX5, DDX5, ddx5 gene protein, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (Asp-Glu-Ala-Asp) box helicase 5, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, DEAD box protein 5, DEAD box RNA helicase DEAD1, DEAD box-5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD), DEAD-box helicase 5, DKFZp434E109, DKFZp686J01190, G17P1, HELR, Hlr1, HUMP68, mDEAD1, MGC118083, p68, p68 RNA helicase, PCR product with interspecies-compatible primers, probable ATP-dependent RNA helicase DDX5, RNA helicase p68, RP23-247J12.4
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
DDX5
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P17844
Gene Symbols:
DDX5
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1655
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
Ab204
Conjugate:
Alexa Fluor 488
Gene:
DDX5
Gene Alias:
2600009A06Rik, ATP-dependent RNA helicase DDX5, DDX5, ddx5 gene protein, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 5, DEAD (Asp-Glu-Ala-Asp) box helicase 5, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, DEAD box protein 5, DEAD box RNA helicase DEAD1, DEAD box-5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD), DEAD-box helicase 5, DKFZp434E109, DKFZp686J01190, G17P1, HELR, Hlr1, HUMP68, mDEAD1, MGC118083, p68, p68 RNA helicase, PCR product with interspecies-compatible primers, probable ATP-dependent RNA helicase DDX5, RNA helicase p68, RP23-247J12.4
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CX3CR1
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P49238
Gene Symbols: CX3CR1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1524
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry
Clone: 2A9-1
Conjugate: Alexa Fluor 488
Gene: CX3CR1
Gene Alias: Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28
Host Species: Rat
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CX3CR1
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P49238
Gene Symbols:
CX3CR1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1524
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
2A9-1
Conjugate:
Alexa Fluor 488
Gene:
CX3CR1
Gene Alias:
Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, Cx3c, CX3C chemokine receptor 1, C-X3-C CKR-1, C-X3-C motif chemokine receptor 1, Cx3cr1, Fractalkine receptor, G protein-coupled receptor 13, GPR13, G-protein coupled receptor 13, GPRV28, RBS11, Scyd1, V28
Host Species:
Rat
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ