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5316813

Human/Mouse BACE-1 Ectodomain Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 6 publications

Manufacturer: Fischer Scientific

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Antigen

BACE-1

Concentration

LYOPH

Applications

Western Blot, Immunohistochemistry, Flow Cytometry, CyTOF

Conjugate

Unconjugated

Regulatory Status

RUO

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Alias

APP beta-secretase, ASP2, Aspartyl protease 2, BACE1, BACEAsp 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1, EC 3.4.23, EC 3.4.23.46, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2

Gene Symbols

BACE1

Isotype

IgG1

Purification Method

Protein A or G purified from hybridoma culture supernatant

Content And Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Clone

137612

Dilution

Western Blot 2 ug/mL, Immunohistochemistry 8-25 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, CyTOF-ready

Classification

Monoclonal

Host Species

Mouse

Target Species

Human, Mouse

Gene Accession No.

P56817

Gene ID (Entrez)

23621

Immunogen

Mouse myeloma cell line NS0-derived recombinant human BACE-1 Thr22-Tyr460 Accession # P56817

Primary or Secondary

Primary

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity

Detects human and mouse BACE-1 in direct ELISAs and human BACE-1 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) BACE-2, recombinant mouse (rm) BACE-2, rhADAM8, rmADAM9, rmADAM10, rhADAM15, or rhTACE is observed.

Description

  • BACE-1 Monoclonal specifically detects BACE-1 in Human, Mouse samples
  • It is validated for Western Blot, Immunohistochemistry, Intracellular Staining by Flow Cytometry, CyTOF-ready.

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Img

Fischer Scientific

5316813

Mouse Monoclonal Antibody has been ...

Antigen:
BACE-1
Concentration:
LYOPH
Applications:
Western Blot, Immunohistochemistry, Flow Cytometry, CyTOF
Conjugate:
Unconjugated
Regulatory Status:
RUO
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Alias:
APP beta-secretase, ASP2, Aspartyl protease 2, BACE1, BACEAsp 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1, EC 3.4.23, EC 3.4.23.46, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2
Gene Symbols:
BACE1
Isotype:
IgG1
Purification Method:
Protein A or G purified from hybridoma culture supernatant
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Clone:
137612
Dilution:
Western Blot 2 ug/mL, Immunohistochemistry 8-25 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, CyTOF-ready
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
P56817
Gene ID (Entrez):
23621
Immunogen:
Mouse myeloma cell line NS0-derived recombinant human BACE-1 Thr22-Tyr460 Accession # P56817
Primary or Secondary:
Primary
Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.
Test Specificity:
Detects human and mouse BACE-1 in direct ELISAs and human BACE-1 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) BACE-2, recombinant mouse (rm) BACE-2, rhADAM8, rmADAM9, rmADAM10, rhADAM15, or rhTACE is observed.

Img

Fischer Scientific

5316815

Mouse Monoclonal Antibody has been ...

Antigen:
Betacellulin/BTC
Concentration:
__
Applications:
ELISA
Conjugate:
Unconjugated
Regulatory Status:
RUO
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Alias:
betacellulin, BTC, probetacellulin
Gene Symbols:
BTC
Isotype:
IgG1
Purification Method:
Protein A or G purified from ascites
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Clone:
34362
Dilution:
ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P35070
Gene ID (Entrez):
685
Immunogen:
E. coli-derived recombinant human Betacellulin Asp32-Tyr111 Accession # P35070
Primary or Secondary:
Primary
Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.
Test Specificity:
Detects human Betacellulin in ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) EGF, rhHB-EGF, rhTGF-alpha , rhHRG-alpha , or rhAR under non-reducing conditions.

Img

Fischer Scientific

5316815

Mouse Monoclonal Antibody has been ...

Antigen:
Betacellulin/BTC
Concentration:
__
Applications:
ELISA
Conjugate:
Unconjugated
Regulatory Status:
RUO
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Alias:
betacellulin, BTC, probetacellulin
Gene Symbols:
BTC
Isotype:
IgG1
Purification Method:
Protein A or G purified from ascites
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Clone:
34362
Dilution:
ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P35070
Gene ID (Entrez):
685
Immunogen:
E. coli-derived recombinant human Betacellulin Asp32-Tyr111 Accession # P35070
Primary or Secondary:
Primary
Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.
Test Specificity:
Detects human Betacellulin in ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) EGF, rhHB-EGF, rhTGF-alpha , rhHRG-alpha , or rhAR under non-reducing conditions.

Img

Fischer Scientific

5316816

Mouse Monoclonal Antibody has been ...

Antigen:
BMP-7
Concentration:
__
Applications:
Western Blot, Immunohistochemistry, Neutralization
Conjugate:
Unconjugated
Regulatory Status:
RUO
Formulation:
Supplied as a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Alias:
BMP7, BMP-7, bone morphogenetic protein 7, Eptotermin alfa, OP-1, OP-1OP1, Osteogenic protein 1
Gene Symbols:
BMP7
Isotype:
IgG2b
Purification Method:
Protein A or G purified from hybridoma culture supernatant
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC, as supplied. 1 month, 2 to 8 degreesC under sterile conditions after opening. 6 months, -20 to -70 degreesC under sterile conditions after opening.
Clone:
164311
Dilution:
Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Neutralization 1.5-6.0 ug/mL
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P18075
Gene ID (Entrez):
655
Immunogen:
Chinese hamster ovary cell line CHO-derived recombinant human BMP-7 Ser293-His431 Accession # P18075
Primary or Secondary:
Primary
Reconstitution:
__
Test Specificity:
Detects human BMP-7 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) BMP-6 is observed and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8 is observed.