5317095

Human TACE/ADAM17 Ectodomain Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 11 publications

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

TACE/ADAM17

Concentration

LYOPH

Applications

Western Blot, Flow Cytometry, Immunoprecipitation, CyTOF, KnockDown

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P78536

Gene ID (Entrez)

6868

Immunogen

Insect ovarian cell lineT. ni-derived recombinant human TACE/ADAM17 Pro18-Asn671 Accession # P78536

Primary or Secondary

Primary

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity

Detects the ectodomain of human TACE/ADAM17 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with the ectodomain of recombinant human ADAM8, 9, 15 and recombinant mouse ADAM10 is observed.

Clone

111633

Dilution

Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunoprecipitation 25 ug/mL, CyTOF-ready, Knockout Validated 0.25 ug/10^6 cells

Classification

Monoclonal

Form

Ascites

Regulatory Status

RUO

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Alias

ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, ADAM17, ADAM18, CD156b, CD156b antigen, CSVP, disintegrin and metalloproteinase domain-containing protein 17, EC 3.4.24.86, MGC71942, Snake venom-like protease, TACEcSVP, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme

Gene Symbols

ADAM17

Isotype

IgG1

Purification Method

Protein A or G purified from ascites

Content And Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Description

  • TACE/ADAM17 Monoclonal specifically detects TACE/ADAM17 in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunoprecipitation, CyTOF-ready, Knockout Validated.

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Fischer Scientific

5317095

Mouse Monoclonal Antibody has been ...


Antigen:
TACE/ADAM17

Concentration:
LYOPH

Applications:
Western Blot, Flow Cytometry, Immunoprecipitation, CyTOF, KnockDown

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P78536

Gene ID (Entrez):
6868

Immunogen:
Insect ovarian cell lineT. ni-derived recombinant human TACE/ADAM17 Pro18-Asn671 Accession # P78536

Primary or Secondary:
Primary

Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity:
Detects the ectodomain of human TACE/ADAM17 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with the ectodomain of recombinant human ADAM8, 9, 15 and recombinant mouse ADAM10 is observed.

Clone:
111633

Dilution:
Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunoprecipitation 25 ug/mL, CyTOF-ready, Knockout Validated 0.25 ug/10^6 cells

Classification:
Monoclonal

Form:
Ascites

Regulatory Status:
RUO

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Alias:
ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, ADAM17, ADAM18, CD156b, CD156b antigen, CSVP, disintegrin and metalloproteinase domain-containing protein 17, EC 3.4.24.86, MGC71942, Snake venom-like protease, TACEcSVP, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme

Gene Symbols:
ADAM17

Isotype:
IgG1

Purification Method:
Protein A or G purified from ascites

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Img

Fischer Scientific

5317096

Mouse Monoclonal Antibody has been ...


Antigen:
TACI/TNFRSF13B/CVID

Concentration:
__

Applications:
Western Blot, Immunohistochemistry, Blockade of Receptor-ligand Interaction, ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O14836

Gene ID (Entrez):
23495

Immunogen:
Mouse myeloma cell line NS0-derived recombinant human TACI/TNFRSF13B Ser2-Thr166 Accession # O14836

Primary or Secondary:
Primary

Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity:
Detects human TACI/TNFRSF13B in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse TACI or recombinant human BCMA is observed.

Clone:
165609

Dilution:
Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Blockade of Receptor-ligand Interaction, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

Classification:
Monoclonal

Form:
__

Regulatory Status:
RUO

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Alias:
CD267, CD267 antigen, CVID, CVID2, FLJ39942, MGC133214, TACIMGC39952, TNFRSF13B, TNFRSF14B, Transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B, tumor necrosis factor receptor superfamily member 13B, tumor necrosis factor receptor superfamily, member 13B

Gene Symbols:
TNFRSF13B

Isotype:
IgG1

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Img

Fischer Scientific

5317098

Mouse Monoclonal Antibody has been ...


Antigen:
TGF-beta 1

Concentration:
__

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Multi-species

Gene Accession No.:
__

Gene ID (Entrez):
7040

Immunogen:
Chinese hamster ovary cell line CHO-derived recombinant human TGF-beta 1

Primary or Secondary:
Primary

Reconstitution:
Reconstitute at 0.5 mg/mL in sterile PBS.

Test Specificity:
Detects multiple species of TGF-beta 1 in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) TGF-alpha , rhTGF-beta 2, rhTGF-beta 3, rhTGF-beta 5, rhLAP (TGF-beta 1), rhART, rhNeurturin, or recombinant mouse TRANCE.

Clone:
141322

Dilution:
Western Blot 1 ug/mL

Classification:
Monoclonal

Form:
__

Regulatory Status:
RUO

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Alias:
CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1, TGFB, TGFB1, TGFbeta, TGFbeta 1, TGF-beta 1 protein, TGF-beta-1, transforming growth factor beta-1, transforming growth factor, beta 1

Gene Symbols:
TGFB1

Isotype:
IgG2b

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

Img

Fischer Scientific

5317099

Rat Monoclonal Antibody has been us...


Antigen:
TGF-beta 2

Concentration:
__

Applications:
Neutralization

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P27090

Gene ID (Entrez):
7042

Immunogen:
Chinese hamster ovary cell line CHO-derived recombinant mouse TGF-beta 2 Ala303-Ser414 Accession # P27090

Primary or Secondary:
Primary

Reconstitution:
Sterile PBS to a final concentration of 0.5 mg/mL.

Test Specificity:
Detects mouse TGF-beta 2 in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant human (rh) TGF-beta 2 and rhTGF-beta 3 is observed.

Clone:
771213

Dilution:
Neutralization 0.15-0.75 ug/mL

Classification:
Monoclonal

Form:
__

Regulatory Status:
RUO

Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative

Gene Alias:
BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, MGC116892, Polyergin, TGFB2, TGFbeta 2, TGF-beta2, TGF-beta-2, transforming growth factor beta-2, transforming growth factor, beta 2

Gene Symbols:
TGFB2

Isotype:
IgG2b

Purification Method:
Protein A or G purified from hybridoma culture supernatant

Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.