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5323525

CD46 Antibody (122.2), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD46

Concentration

0.2mg/mL

Applications

Flow Cytometry, SDS-Page, Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cancer, Cell Biology, Cellular Markers, Immunology

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

Gene Symbols

CD46

Isotype

IgG1 κ

Purification Method

Protein G purified

Test Specificity

CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Clone

122.2

Dilution

Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Accession No.

NP_002380

Gene ID (Entrez)

4179

Immunogen

A recombinant protein fragment specific for human CD46 was used as the immunogen.

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Description

  • CD46 Monoclonal specifically detects CD46 in Human samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Functional, Immunofluorescence.

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Fischer Scientific

5323525

Mouse Monoclonal Antibody...

Antigen:
CD46
Concentration:
0.2mg/mL
Applications:
Flow Cytometry, SDS-Page, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Gene Symbols:
CD46
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Clone:
122.2
Dilution:
Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
NP_002380
Gene ID (Entrez):
4179
Immunogen:
A recombinant protein fragment specific for human CD46 was used as the immunogen.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.

Img

Sigma Aldrich

532355

98%...

Antigen:
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Concentration:
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Applications:
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Conjugate:
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Host Species:
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Research Discipline:
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Formulation:
__
Gene Alias:
__
Gene Symbols:
__
Isotype:
__
Purification Method:
__
Test Specificity:
__
Clone:
__
Dilution:
__
Classification:
__
Form:
__
Regulatory Status:
__
Target Species:
__
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
__

Img

Fischer Scientific

5323561

Mouse Monoclonal Antibody...

Antigen:
CD48/SLAMF2
Concentration:
0.5 mg/mL
Applications:
Flow Cytometry
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cell Biology, Cellular Markers, Immunology, Stem Cell Markers
Formulation:
Aqueous, may contain carrier protein/stabilizer. with 0.09% Sodium Azide
Gene Alias:
BCM1 surface antigen, BCM1Leukocyte antigen MEM-102, BLAST, BLAST1TCT.1, B-lymphocyte activation marker BLAST-1, CD48 antigen, CD48 antigen (B-cell membrane protein), CD48 molecule, hCD48, mCD48, MEM-102, SLAMF2
Gene Symbols:
CD48
Isotype:
IgG1
Purification Method:
Affinity Purified
Test Specificity:
__
Clone:
156-4H9
Dilution:
Flow Cytometry 1:10-1:1000
Classification:
Monoclonal
Form:
__
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
__
Gene ID (Entrez):
962
Immunogen:
The immunogen for this antibody was CD48.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C. Do not freeze.

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5323577

Mouse Monoclonal Antibody has been ...

Antigen:
Calnexin
Concentration:
1.0 mg/mL
Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
ER Markers, Neuroscience, Phospho Specific, Sensory Systems, Unfolded Protein Response, Vision
Formulation:
PBS with 0.05% Sodium Azide
Gene Alias:
calnexin, CNX, IP90FLJ26570, Major histocompatibility complex class I antigen-binding protein p88, P90
Gene Symbols:
CANX
Isotype:
IgG2b κ
Purification Method:
Protein G purified
Test Specificity:
Immunogen's sequence similarity with other species: Mouse (88%), Duck (81%), Xenopus (76%)
Clone:
1C2.2D11
Dilution:
Western Blot, Immunohistochemistry 7 ug/ml, Immunocytochemistry/Immunofluorescence 10 ug/ml, Immunohistochemistry-Paraffin 7 ug/ml, Flow (Intracellular) 5 ug/million cells
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
P27824
Gene ID (Entrez):
821
Immunogen:
Partial recombinant human Calnexin protein (between amino acids 1-300). [UniProt P27824]
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.