5326033
Carbonic Anhydrase IX/CA9 Antibody (66.4.C2 (PN-15)), Novus Biologicals™
Mouse Monoclonal Antibody has been used in 5 publications
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Renal Cell Carcinoma (gp200)
Concentration
0.2mg/mL
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Formulation
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias
CD205LY-75, CLEC13BLy-75, C-type lectin domain family 13 member B, DEC-205CD205 antigen, GP200-MR6, lymphocyte antigen 75
Gene Symbols
LY75
Isotype
IgG2b κ
Purification Method
Protein G purified
Test Specificity
Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Clone
66.4.C2 (PN-15)
Dilution
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Dendritic Cell Markers, Ovarian Carcinoma Cell Markers, Renal Cell Carcinoma Cell Markers
Gene Accession No.
Q16790
Gene ID (Entrez)
4065
Immunogen
Fresh, normal human renal cortical tissue homogenate was used as immunogen to generate the RCC antibody.
Primary or Secondary
Primary
Content And Storage
Store at 4C.
Description
- Carbonic Anhydrase IX/CA9 Monoclonal specifically detects Carbonic Anhydrase IX/CA9 in Human, Equine samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
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Antigen: Renal Cell Carcinoma (gp200)
Concentration: 0.2mg/mL
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: CD205LY-75, CLEC13BLy-75, C-type lectin domain family 13 member B, DEC-205CD205 antigen, GP200-MR6, lymphocyte antigen 75
Gene Symbols: LY75
Isotype: IgG2b κ
Purification Method: Protein G purified
Test Specificity: Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Clone: 66.4.C2 (PN-15)
Dilution: Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Dendritic Cell Markers, Ovarian Carcinoma Cell Markers, Renal Cell Carcinoma Cell Markers
Gene Accession No.: Q16790
Gene ID (Entrez): 4065
Immunogen: Fresh, normal human renal cortical tissue homogenate was used as immunogen to generate the RCC antibody.
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen:
Renal Cell Carcinoma (gp200)
Concentration:
0.2mg/mL
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias:
CD205LY-75, CLEC13BLy-75, C-type lectin domain family 13 member B, DEC-205CD205 antigen, GP200-MR6, lymphocyte antigen 75
Gene Symbols:
LY75
Isotype:
IgG2b κ
Purification Method:
Protein G purified
Test Specificity:
Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Clone:
66.4.C2 (PN-15)
Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Dendritic Cell Markers, Ovarian Carcinoma Cell Markers, Renal Cell Carcinoma Cell Markers
Gene Accession No.:
Q16790
Gene ID (Entrez):
4065
Immunogen:
Fresh, normal human renal cortical tissue homogenate was used as immunogen to generate the RCC antibody.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Antigen: EEA1
Concentration: 1.0 mg/mL
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS with 0.02% Sodium Azide
Gene Alias: early endosome antigen 1, early endosome antigen 1, 162kD, early endosome-associated protein, Endosome-associated protein p162, MSTP105, ZFYVE2, ZFYVE2MST105, Zinc finger FYVE domain-containing protein 2
Gene Symbols: EEA1
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: __
Clone: 6D4.1D4
Dilution: Western Blot, Immunohistochemistry 5-10 ug/ml, Immunocytochemistry/Immunofluorescence reported in scientific literature (PMID 33212210), Immunohistochemistry-Paraffin 5-10 ug/ml, Flow (Intracellular) 2.5 ug/million cells
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Endosome Markers, Membrane Trafficking and Chaperones
Gene Accession No.: Q15075
Gene ID (Entrez): 8411
Immunogen: Partial recombinant human EEA1 protein (between amino acids 50-300). [UniProt Q15075]
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen:
EEA1
Concentration:
1.0 mg/mL
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
PBS with 0.02% Sodium Azide
Gene Alias:
early endosome antigen 1, early endosome antigen 1, 162kD, early endosome-associated protein, Endosome-associated protein p162, MSTP105, ZFYVE2, ZFYVE2MST105, Zinc finger FYVE domain-containing protein 2
Gene Symbols:
EEA1
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
__
Clone:
6D4.1D4
Dilution:
Western Blot, Immunohistochemistry 5-10 ug/ml, Immunocytochemistry/Immunofluorescence reported in scientific literature (PMID 33212210), Immunohistochemistry-Paraffin 5-10 ug/ml, Flow (Intracellular) 2.5 ug/million cells
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Endosome Markers, Membrane Trafficking and Chaperones
Gene Accession No.:
Q15075
Gene ID (Entrez):
8411
Immunogen:
Partial recombinant human EEA1 protein (between amino acids 50-300). [UniProt Q15075]
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Antigen: EpCAM/TROP1
Concentration: 0.2mg/mL
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: 17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A
Gene Symbols: EPCAM
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: This antibody reacts with the first EGF repeat in the extracellular domain of Ep-CAM. It is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
Clone: VU-1D9
Dilution: Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cancer
Gene Accession No.: P16422
Gene ID (Entrez): 4072
Immunogen: Small cell lung carcinoma cells
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen:
EpCAM/TROP1
Concentration:
0.2mg/mL
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A
Gene Symbols:
EPCAM
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
This antibody reacts with the first EGF repeat in the extracellular domain of Ep-CAM. It is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
Clone:
VU-1D9
Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cancer
Gene Accession No.:
P16422
Gene ID (Entrez):
4072
Immunogen:
Small cell lung carcinoma cells
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Antigen: ER alpha/NR3A1
Concentration: 0.2mg/mL
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
Gene Symbols: ESR1
Isotype: IgG1 κ
Purification Method: Protein G purified
Test Specificity: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.
Clone: ER505
Dilution: Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 1-2ug/ml, SDS-Page
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: __
Gene Accession No.: __
Gene ID (Entrez): 2099
Immunogen: Recombinant human Estrogen Receptor alpha protein (aa2-185)
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Antigen:
ER alpha/NR3A1
Concentration:
0.2mg/mL
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias:
ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
Gene Symbols:
ESR1
Isotype:
IgG1 κ
Purification Method:
Protein G purified
Test Specificity:
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.
Clone:
ER505
Dilution:
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 1-2ug/ml, SDS-Page
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
__
Gene Accession No.:
__
Gene ID (Entrez):
2099
Immunogen:
Recombinant human Estrogen Receptor alpha protein (aa2-185)
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.