5378091

HLA-DR Mouse anti-Human, APC-R700, Clone: G46-6, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

HLA-DR

Applications

Flow Cytometry

Conjugate

APC-R700

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

G46-6

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

MHC class II antigen; HLA class II histocompatibility antigen

Description

  • Description The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen
  • HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6
  • HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells
  • HLA-DR is also expressed on activated T cells
  • This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

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Mouse Monoclonal Antibody...


Antigen:
HLA-DR

Applications:
Flow Cytometry

Conjugate:
APC-R700

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
G46-6

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
MHC class II antigen; HLA class II histocompatibility antigen

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