55-930-4200UL
MilliporeSigma™ anti-SAPK/JNK, Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 55-930-4200UL-Each-of-1 | In Stock | ₹ 49,963.62 |
55-930-4200UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,963.62
GST (18%): ₹ 8,993.452
Total Price: ₹ 58,957.072
Antigen
SAPK/JNK
Classification
Polyclonal
Formulation
In 150mM NaCl, 10mM HEPES, 50% glycerol, 0.01% BSA, pH 7.5.
Immunogen
a full-length, recombinant, human p54 SAPK/JNK2 fusion protein
Regulatory Status
RUO
Test Specificity
Recognizes the ∽54kDa SAPK/JNK protein in uv-treated HEK293 cells.
Content And Storage
−20°C
Isotype
IgG
Applications
Immunocytochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects SAPK/JNK Clone: in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry The Stress-activated protein kinases (SAPK), also referred to as Jun N-terminal kinases (JNK), function in a protein kinase cascade transducing cellular stress signals
- SAPK/JNKs are activated by a highly diverse group of extracellular signals, including UV light, inflammatory cytokines and a wide variety of cellular stresses
- Activation occurs via phosphorylation at Thr 183 and Tyr 185 by the dual specificity enzyme SEK/MKK4 and as yet unidentified kinases
- Since dual phosphorylation of SAPK/JNK at Thr 183 /Tyr 185 is essential for kinase activity, phosphorylation at this site is an excellent marker of SAPK/JNK activity
- Activated SAPK in turn phosphorylates and activates several transcription factors, including c- jun at Ser 63/73 and ATF-2 at Ser 69/71 .
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Antigen: SAPK/JNK
Classification: Polyclonal
Formulation: In 150mM NaCl, 10mM HEPES, 50% glycerol, 0.01% BSA, pH 7.5.
Immunogen: a full-length, recombinant, human p54 SAPK/JNK2 fusion protein
Regulatory Status: RUO
Test Specificity: Recognizes the ∽54kDa SAPK/JNK protein in uv-treated HEK293 cells.
Content And Storage: −20°C
Isotype: IgG
Applications: Immunocytochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
SAPK/JNK
Classification:
Polyclonal
Formulation:
In 150mM NaCl, 10mM HEPES, 50% glycerol, 0.01% BSA, pH 7.5.
Immunogen:
a full-length, recombinant, human p54 SAPK/JNK2 fusion protein
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽54kDa SAPK/JNK protein in uv-treated HEK293 cells.
Content And Storage:
−20°C
Isotype:
IgG
Applications:
Immunocytochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: PhosphoDetect™ SAPK/JNK (pThr183, Tyr185)
Classification: Polyclonal
Formulation: In Dulbecco's PBS (without Mg2+and Ca2+), 50% glycerol, 1mg/mL BSA, pH 7.3.
Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Thr183and Tyr185phosphorylation sites of human SAPK/JNK
Regulatory Status: RUO
Test Specificity: Recognizes the ∽49kDa SAPK1 protein and the ∽55kDa SAPK2 protein phosphorylated at Thr183and Tyr185. Antibody Target Gene Symbol: MAPK8, MAPK9 Target Synonym: AI849689, C-JUN N-TERMINAL KINASE1, JNK, JNK1, JNK1 PROTEIN KINASE, JNK1A2, JNK21B1/2, p46JNK1, p46JNK1 ALPHA, PRKM8, Sapk gamma, SAPK P46, SAPK1, SAPK1/JNK, STRESS-ACTIVATED PROTEIN KINASE-LIKE KINASE, AI851083, Jnk p54, Jnk p55, JNK-55, JNK2, JNK2A, Jnk2a2, JNK2ALPHA, JNK2B, JNK2BETA, JUNKINASE, p54a, p54aSAPK, PRKM9, SAPK, SAPK ALPHA, SAPK ALPHA 1 Entrez Gene Name: mitogen-activated protein kinase 8
Content And Storage: ≤ -70°C
Isotype: IgG
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: C. elegans, Chicken, Drosophila, Human, Mouse, Rat
Form: Purified
Antigen:
PhosphoDetect™ SAPK/JNK (pThr183, Tyr185)
Classification:
Polyclonal
Formulation:
In Dulbecco's PBS (without Mg2+and Ca2+), 50% glycerol, 1mg/mL BSA, pH 7.3.
Immunogen:
a synthetic phosphopeptide corresponding to amino acids surrounding the Thr183and Tyr185phosphorylation sites of human SAPK/JNK
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽49kDa SAPK1 protein and the ∽55kDa SAPK2 protein phosphorylated at Thr183and Tyr185. Antibody Target Gene Symbol: MAPK8, MAPK9 Target Synonym: AI849689, C-JUN N-TERMINAL KINASE1, JNK, JNK1, JNK1 PROTEIN KINASE, JNK1A2, JNK21B1/2, p46JNK1, p46JNK1 ALPHA, PRKM8, Sapk gamma, SAPK P46, SAPK1, SAPK1/JNK, STRESS-ACTIVATED PROTEIN KINASE-LIKE KINASE, AI851083, Jnk p54, Jnk p55, JNK-55, JNK2, JNK2A, Jnk2a2, JNK2ALPHA, JNK2B, JNK2BETA, JUNKINASE, p54a, p54aSAPK, PRKM9, SAPK, SAPK ALPHA, SAPK ALPHA 1 Entrez Gene Name: mitogen-activated protein kinase 8
Content And Storage:
≤ -70°C
Isotype:
IgG
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
C. elegans, Chicken, Drosophila, Human, Mouse, Rat
Form:
Purified
Antigen: __
Classification: __
Formulation: __
Immunogen: __
Regulatory Status: __
Test Specificity: __
Content And Storage: Protect from light
Isotype: __
Applications: __
Conjugate: __
Host Species: __
Quantity: 1 mg
Primary or Secondary: __
Target Species: __
Form: Solid
Antigen:
__
Classification:
__
Formulation:
__
Immunogen:
__
Regulatory Status:
__
Test Specificity:
__
Content And Storage:
Protect from light
Isotype:
__
Applications:
__
Conjugate:
__
Host Species:
__
Quantity:
1 mg
Primary or Secondary:
__
Target Species:
__
Form:
Solid
Antigen: __
Classification: __
Formulation: __
Immunogen: __
Regulatory Status: __
Test Specificity: __
Content And Storage: Protect from light
Isotype: __
Applications: __
Conjugate: __
Host Species: __
Quantity: 10 mg
Primary or Secondary: __
Target Species: __
Form: Thin Film
Antigen:
__
Classification:
__
Formulation:
__
Immunogen:
__
Regulatory Status:
__
Test Specificity:
__
Content And Storage:
Protect from light
Isotype:
__
Applications:
__
Conjugate:
__
Host Species:
__
Quantity:
10 mg
Primary or Secondary:
__
Target Species:
__
Form:
Thin Film