5533400
MilliporeSigma™ Mouse anti-CD8a, Clone: RPA-T8, PE,
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD8a
Applications
Flow Cytometry
Conjugate
PE
Host Species
Mouse
Research Discipline
Inflammation and Immunology
Formulation
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols
CD8A; MAL
Primary or Secondary
Primary
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone
RPA-T8
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human
Gene Accession No.
P01732
Immunogen
Immunogen information for this antibody is proprietary information.
Purification Method
Purified by size-exclusion chromatography
Description
- Specifically detects CD8a clone: RPA-T8 in Human samples, and it is validated for Flow Cytometry The RPA-T8 antibody is specific for the 32-34kDa alpha chain of human CD8, known as CD8a or CD8 alpha
- CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta
- CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules
- The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions
- CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.The RPA-T8 antibody is widely used as a phenotypic marker for CD8 on cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR, including some NK cells and lymphoid dendritic cells
- It is cross-reactive with CD8 in several non-human species, including Baboon, Chimpanzee, Cynomolgus and Rhesus
- If used together with an alternative Anti-Human CD8a clone, Hit8a, the RPA-T8 antibody will not block binding of Hit8a to CD8a.
Compare Similar Items
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Antigen: CD8a
Applications: Flow Cytometry
Conjugate: PE
Host Species: Mouse
Research Discipline: Inflammation and Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: CD8A; MAL
Primary or Secondary: Primary
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone: RPA-T8
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: P01732
Immunogen: Immunogen information for this antibody is proprietary information.
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD8a
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Mouse
Research Discipline:
Inflammation and Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
CD8A; MAL
Primary or Secondary:
Primary
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone:
RPA-T8
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
P01732
Immunogen:
Immunogen information for this antibody is proprietary information.
Purification Method:
Purified by size-exclusion chromatography
Antigen: CD20
Applications: Flow Cytometry
Conjugate: PE
Host Species: Mouse
Research Discipline: Inflammation and Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: MS4A1; CD20
Primary or Secondary: Primary
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone: 2H7
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: P11836
Immunogen: Immunogen information for this antibody is proprietary information.
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD20
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Mouse
Research Discipline:
Inflammation and Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
MS4A1; CD20
Primary or Secondary:
Primary
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone:
2H7
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
P11836
Immunogen:
Immunogen information for this antibody is proprietary information.
Purification Method:
Purified by size-exclusion chromatography
Antigen: CD20
Applications: Flow Cytometry
Conjugate: PE
Host Species: Mouse
Research Discipline: Inflammation and Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: MS4A1; CD20
Primary or Secondary: Primary
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone: 2H7
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: P11836
Immunogen: Immunogen information for this antibody is proprietary information.
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD20
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Mouse
Research Discipline:
Inflammation and Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
MS4A1; CD20
Primary or Secondary:
Primary
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone:
2H7
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
P11836
Immunogen:
Immunogen information for this antibody is proprietary information.
Purification Method:
Purified by size-exclusion chromatography
Antigen: CD45
Applications: Flow Cytometry
Conjugate: Red Fluor 710
Host Species: Mouse
Research Discipline: Inflammation and Immunology
Formulation: Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols: Ptprc; Ly-5
Primary or Secondary: Primary
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone: HI30
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Accession No.: P06800
Immunogen: Immunogen information for this antibody is proprietary information.
Purification Method: Purified by size-exclusion chromatography
Antigen:
CD45
Applications:
Flow Cytometry
Conjugate:
Red Fluor 710
Host Species:
Mouse
Research Discipline:
Inflammation and Immunology
Formulation:
Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Symbols:
Ptprc; Ly-5
Primary or Secondary:
Primary
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Clone:
HI30
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Accession No.:
P06800
Immunogen:
Immunogen information for this antibody is proprietary information.
Purification Method:
Purified by size-exclusion chromatography