5539124

beta 2-Microglobulin Antibody (B2M/1118), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

beta 2-Microglobulin

Concentration

0.2mg/mL

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Gene Symbols

B2M

Isotype

IgG1 κ

Purification Method

Protein A or G purified

Test Specificity

beta 2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta 2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).

Clone

B2M/1118

Dilution

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Primate

Gene Accession No.

P61769

Gene ID (Entrez)

567

Immunogen

Full length recombinant human B2M protein

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Molecular Weight of Antigen

12 kDa

Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

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Fischer Scientific

5539124

Mouse Monoclonal Antibody...


Antigen:
beta 2-Microglobulin

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Gene Symbols:
B2M

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
beta 2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta 2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).

Clone:
B2M/1118

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Primate

Gene Accession No.:
P61769

Gene ID (Entrez):
567

Immunogen:
Full length recombinant human B2M protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
12 kDa

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553913

powder, −100 mesh, ≥99% trace metal...


Antigen:
__

Concentration:
__

Applications:
__

Conjugate:
__

Host Species:
__

Research Discipline:
__

Formulation:
__

Gene Alias:
__

Gene Symbols:
__

Isotype:
__

Purification Method:
__

Test Specificity:
__

Clone:
__

Dilution:
__

Classification:
__

Form:
__

Regulatory Status:
__

Target Species:
__

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
__

Primary or Secondary:
__

Content And Storage:
__

Molecular Weight of Antigen:
__

Img

Fischer Scientific

5539133

Mouse Monoclonal Antibody...


Antigen:
beta-1,3-Glucuronyltransferase 1/B3GAT1

Concentration:
0.2mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Immunology

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Beta-1,3-glucuronyltransferase 1, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P), EC 2.4.1.135, galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, GlcAT-P, GLCATPGLCUATP, glcUAT-P, Glucuronosyltransferase P, NK1, NK-1, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase

Gene Symbols:
B3GAT1

Isotype:
IgM

Purification Method:
Protein A or G purified

Test Specificity:
Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Clone:
HNK-1 + NK-1

Dilution:
Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Rat (Negative)

Gene Accession No.:
Q9P2W7

Gene ID (Entrez):
27087

Immunogen:
Human peripheral blood mononuclear cells (HNK-1 and NK-1)

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
__

Img

Fischer Scientific

5539133

Mouse Monoclonal Antibody...


Antigen:
beta-1,3-Glucuronyltransferase 1/B3GAT1

Concentration:
0.2mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Immunology

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Beta-1,3-glucuronyltransferase 1, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P), EC 2.4.1.135, galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, GlcAT-P, GLCATPGLCUATP, glcUAT-P, Glucuronosyltransferase P, NK1, NK-1, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase

Gene Symbols:
B3GAT1

Isotype:
IgM

Purification Method:
Protein A or G purified

Test Specificity:
Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Clone:
HNK-1 + NK-1

Dilution:
Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Rat (Negative)

Gene Accession No.:
Q9P2W7

Gene ID (Entrez):
27087

Immunogen:
Human peripheral blood mononuclear cells (HNK-1 and NK-1)

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
__