Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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HLA DRA
0.2 mg/mL
Flow Cytometry, SDS-Page, Immunofluorescence
Unconjugated
Mouse
Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
HLA-DRA
IgG2b κ
Protein A or G purified
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
169-1B5.2
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Monoclonal
Purified
RUO
Human, Bovine, Feline
P01903
3122
Human peripheral blood leukocytes
Primary
Store at 4C.