56-937-2100UG

MilliporeSigma™ anti-PhosphoDetect Src (pTyr418) Clone: 9A6,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 56-937-2100UG-Each-of-1 In Stock ₹ 57,239.64

56-937-2100UG - Each of 1

₹ 57,239.64

In Stock

Quantity

1

Base Price: ₹ 57,239.64

GST (18%): ₹ 10,303.135

Total Price: ₹ 67,542.775

Antigen

Src (pTyr418)

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Purified

Applications

ELISA, Immunoblot, Immunoblot, Immunocytochemistry

Clone

9A6

Formulation

Lyophilized from 2X PBS, PEG, sucrose.

Immunogen

a synthetic phosphopeptide corresponding to amino acids surrounding the pTyr418phosphorylation site of human Src

Regulatory Status

RUO

Test Specificity

Recognizes the ∽60kDa Src protein phosphorylated at Tyr418in chick embryo fibroblasts expressing human wild-type Src.

Content And Storage

−20°C

Isotype

IgG1

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Description

  • Specifically detects Src (pTyr 418 ) Clone: 9A6 in Human, Mouse, Rat samples, and it is validated for ELISA, Immunocytochemistry, Immuno Blotting Src belongs to a family of 9 tyrosine kinases which regulate cellular responses to extracellular stimuli
  • Src is a non-receptor protein tyrosine kinase that transduces signals that are involved in the control of a variety of cellular processes such as proliferation, differentiation, motility, and adhesion
  • Src is normally maintained in an inactive state, but can be activated transiently during cellular events such as mitosis, or constitutively by abnormal events such as mutation (i.e
  • v-Src and some human cancers)
  • Src becomes activated upon dephosphorylation of Tyr 527 which leads to a conformational change of the Src molecule
  • This allows binding to other proteins via the SH2 and SH3 domain
  • Activated Src phosphorylates a variety of substrates involved in the mitogenic signaling pathway, cytoskeletal organization, cell-substrate adhesion, cell-cell adhesion, cell-cell communication and RNA processing.

Compare Similar Items

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MilliporeSigma™

56-937-2100UG

--


Antigen:
Src (pTyr418)

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
ELISA, Immunoblot, Immunoblot, Immunocytochemistry

Clone:
9A6

Formulation:
Lyophilized from 2X PBS, PEG, sucrose.

Immunogen:
a synthetic phosphopeptide corresponding to amino acids surrounding the pTyr418phosphorylation site of human Src

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽60kDa Src protein phosphorylated at Tyr418in chick embryo fibroblasts expressing human wild-type Src.

Content And Storage:
−20°C

Isotype:
IgG1

Img

MilliporeSigma™

56-939-3500UG

--


Antigen:
__

Classification:
__

Conjugate:
__

Host Species:
__

Quantity:
500 μg

Primary or Secondary:
__

Target Species:
__

Form:
Solid

Applications:
__

Clone:
__

Formulation:
__

Immunogen:
__

Regulatory Status:
__

Test Specificity:
__

Content And Storage:
Protect from light

Isotype:
__

Img

MilliporeSigma™

56-939-6100UG

--


Antigen:
__

Classification:
__

Conjugate:
__

Host Species:
__

Quantity:
100 μg

Primary or Secondary:
__

Target Species:
__

Form:
Liquid

Applications:
__

Clone:
__

Formulation:
A 1 mM (100μg/214μl) solution of Staurosporine in DMSO.

Immunogen:
__

Regulatory Status:
__

Test Specificity:
__

Content And Storage:
Protect from light

Isotype:
__

Img

MilliporeSigma™

56-940-610MG

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Antigen:
__

Classification:
__

Conjugate:
__

Host Species:
__

Quantity:
10 mg

Primary or Secondary:
__

Target Species:
__

Form:
Powder

Applications:
__

Clone:
__

Formulation:
__

Immunogen:
__

Regulatory Status:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__