56-996-642

Gata-3 Monoclonal Antibody (TWAJ), Alexa Fluor™ 700, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 56-996-642-Each-of-1 In Stock ₹ 37,218.60

56-996-642 - Each of 1

₹ 37,218.60

In Stock

Quantity

1

Base Price: ₹ 37,218.60

GST (18%): ₹ 6,699.348

Total Price: ₹ 43,917.948

Antigen

Gata-3

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.

P23771, P23772

Gene Symbols

GATA3

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14462, 2625, 713840, 733631

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

TWAJ

Conjugate

Alexa Fluor 700

Gene

GATA3

Gene Alias

EGK_19445, GATA binding factor-3, GATA binding protein 3, GATA binding protein-3, GATA3, Gata-3, GATA-binding factor 3, GATA-binding protein 3, HDR, HDRS, jal, MGC2346, MGC5199, MGC5445, Trans-acting T-cell-specific transcription factor GATA-3, Transacting T-cell-specific transcription factor GATA-3

Host Species

Rat

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse, Porcine, Rhesus Monkey

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • Description: The monoclonal antibody TWAJ recognizes mouse and human Gata-3, a member of the Gata family of transcription factors
  • Gata-3 is a T cell-specific transcription factor important for thymic development and Th2 differentiation
  • Expression during embryonic development is found in the central nervous system, skin, mammary glands and kidney
  • During development, the expression of Gata-3 is essential as homozygous knock-out of Gata-3 is embryonic lethal
  • The Gata-3 is also essential for T cell commitment and survival
  • In the thymus, expression is found mainly on the CD4 single positive cells
  • During Th2 differentiation, Gata-3 binds to the IL-4 promoter as well as represses the expression of T-bet, thus inhibiting Th1 differentiation
  • Alternative splice variants have been reported especially in the MCF7 cell line
  • The TWAJ Human/Mouse Gata-3 antibody will recognize both forms (50 and 45 kDa) of the protein
  • Staining with the TWAJ Human/Mouse Gata-3 antibody requires the use of the Foxp3/Transcription Factor Staining Buffer Set (Product No
  • 00-5523-00)
  • Crossreactivity in rhesus monkeys has been published
  • Applications Reported: This TWAJ antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This TWAJ antibody has been pre-diluted and tested by intracellular staining followed by flow cytometric analysis of mouse thymocytes using the Foxp3/Transcription Factor Staining Buffer Set (Product No
  • The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins
  • Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes
  • GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain
  • GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages
  • GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers
  • Labastie et al
  • (1994) cloned the human gene and the 5-prime end of the mouse gene
  • The human gene comprises 6 exons distributed over 17 kb of DNA
  • Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.

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Invitrogen

56-996-642

--


Antigen:
Gata-3

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P23771, P23772

Gene Symbols:
GATA3

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14462, 2625, 713840, 733631

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
TWAJ

Conjugate:
Alexa Fluor 700

Gene:
GATA3

Gene Alias:
EGK_19445, GATA binding factor-3, GATA binding protein 3, GATA binding protein-3, GATA3, Gata-3, GATA-binding factor 3, GATA-binding protein 3, HDR, HDRS, jal, MGC2346, MGC5199, MGC5445, Trans-acting T-cell-specific transcription factor GATA-3, Transacting T-cell-specific transcription factor GATA-3

Host Species:
Rat

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Invitrogen

56-998-342

--


Antigen:
HLA-ABC

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P01889, P04439, P10321

Gene Symbols:
HLA-A, HLA-B, HLA-C

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3105, 3106, 3107

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
W6/32

Conjugate:
Alexa Fluor 700

Gene:
HLA-C

Gene Alias:
A29 protein, alpha chain of MHC class II, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, class I MHC, HLA-B antigen, D6S204, epididymis secretory protein Li 83, H-2K, H2-K, H-2K(d), HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, HLA C, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen C alpha chain, HLA class I histocompatibility antigen Cw-1 alpha chain, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-11 alpha chain-like, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibility antigen, B-82 alpha chain, HLA class I histocompatibility antigen, C alpha chain, HLA class I histocompatibility antigen, Cw-1 alpha chain, HLA class I histocompatibility antigen, Cw-15 alpha chain, HLA class I histocompatibility antigen, Cw-18 alpha chain, HLA locus, HLA molecule, HLAA, HLA-A, HLA-A locus alpha 2 domain, HLA-A null, HLA-A11, HLA-A33, HLA-Aw33.1, HLAB, HLA-B, HLA-B 1502, HLA-B alpha chain, HLA-B alpha chain (B*2706), HLA-B alpha chain (B*5002), HLA-B alpha-chain, HLA-B*45ZJ, HLA-B15, HLA-B35, HLA-B35 antigen, HLA-B-3506, HLA-B39, HLA-B-3905, HLA-B49, HLA-B50, HLA-B55, HLA-B-5502, HLA-B-5602, HLA-B59, HLA-B61, HLA-Bw50 antigen, HLAC, HLA-C, HLA-C alpha chain, HLA-C alpha chain (HLA-Cw*15v), HLA-C alpha chain for Cw*18GB, HLA-C alpha-chain, HLA-C antigen, HLA-Cw, HLA-Cw*04GB, HLA-Cw*1702, HLA-Cw*18GB, HLA-Cw-1503, HLA-DQB1, HLA-DRB1, HLA-JY3, HLC-C, Human leukocyte antigen A, Human leukocyte antigen C, human leukocyte antigen-C alpha chain, hypothetical protein, lecocyte antigen B, leucocyte antigen A, Leukocyte Antigen, leukocyte antigen C, leukocyte antigen class I-A, leukocyte antigen class I-B, Leukoocyte Antigen, LOC100515902, LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-11 alpha chain-like, lymphocyte antigen, major histocompatability complex B antigen, major histocompatibility antigen HLA-C, major histocompatibility complex, class I, A, major histocompatibility complex, class I, B, major histocompatibility complex, class I, C, MCH class I antigen, MGC184092, MGC7052, MHC, MHC 1, MHC antigen, MHC clas I antigen, MHC Class 1, MHC class 1 antigen, MHC class I, MHC class I alpha chain, MHC class I anitgen, MHC class I anti, MHC Class I antigen, MHC class I antigen A*30, MHC class I antigen A*33, MHC class I antigen A*74, MHC class I antigen B*47, MHC class I antigen B*50, MHC class I antigen B*82, MHC class I antigen Cw*15, MHC class I antigen Cw*18, MHC class I antigen GN00104, MHC class I antigen heavy chain, MHC class I antigen heavy chain HLA-C, MHC class I antigen HLA-A heavy chain, MHC class I antigen HLA-A33, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I antigen null protein, MHC class I antigen SHCHA, MHC class I antigene, MHC class I histocompatibility antigen, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I protein, MHC class II antigen, MHC class l antigen, MHC classI antigen, MHC HLA-ABC, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC HLA-B27d, MHC HLA-B27-HS, MHC HLA-B39N, MHC I HLA, MHC1, PSORS1, SPDA1, surface antigen, truncated class I antigen, truncated MHC class I antigen

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

56-998-641

--


Antigen:
TCR alpha/beta

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01848, P04435, P0DSE1

Gene Symbols:
TRA, TRAC, TRB, TRBV7-9

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
28589, 28755, 6955, 6957

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
IP26

Conjugate:
Alexa Fluor 700

Gene:
TRAC

Gene Alias:
FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA

Host Species:
Mouse

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

56-998-642

--


Antigen:
TCR alpha/beta

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01848, P04435, P0DSE1

Gene Symbols:
TRA, TRAC, TRB, TRBV7-9

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
28589, 28755, 6955, 6957

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
IP26

Conjugate:
Alexa Fluor 700

Gene:
TRAC

Gene Alias:
FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ