61-020-550UG

MilliporeSigma™ anti-Tie2 Clone: Ab33,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 61-020-550UG-Each-of-1 In Stock ₹ 31,368.01

61-020-550UG - Each of 1

₹ 31,368.01

In Stock

Quantity

1

Base Price: ₹ 31,368.01

GST (18%): ₹ 5,646.242

Total Price: ₹ 37,014.252

Antigen

Tie2

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Porcine, Rat

Form

Purified

Applications

Immunoblot, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

Ab33

Formulation

In 150mM NaCl, 70mM Tris-glycine, 30% glycerol, pH 7.4.

Immunogen

a recombinant protein consisting of amino acids 1-745 of human Tie2 fused to a His·Tag™ sequence

Regulatory Status

RUO

Test Specificity

Recognizes the ∽140-45kDa Tie2 protein.

Content And Storage

−20°C

Isotype

IgG1

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Description

  • Specifically detects Tie2 Clone: Ab33 in Human, Mouse, Porcine, Rat samples, and it is validated for Immunohistochemistry (Frozen), Immunoprecipitation, Immuno Blotting Angiopoietin-1 and its naturally occurring inhibitor, angiopoietin-2, exert their effects by inducing autophosphorylation of their signaling receptor Tie2
  • Phosphorylation of the receptor occurs during vasculogenesis and is required for its activity in regulating endothelial cell proliferation, differentiation and guiding the proper patterning of endothelial cells during blood vessel formation
  • Tie-2 is a transmembrane receptor-tyrosine kinase that is expressed by endothelial cells and primitive hematopoietic tissues
  • Tie2/Tek has been shown to be critical for endothelial cell survival, which is evidenced in part by the constitutive phosphorylation that is observed in quiescent endothelium
  • More recently a multifunction docking site has been identified on the receptor (Tyr 1100 ) that serves as a binding site for other partners including Grb2, Grb7, and p85 and acting via an SH2 domain interaction.

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MilliporeSigma™

61-020-550UG

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Antigen:
Tie2

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Form:
Purified

Applications:
Immunoblot, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
Ab33

Formulation:
In 150mM NaCl, 70mM Tris-glycine, 30% glycerol, pH 7.4.

Immunogen:
a recombinant protein consisting of amino acids 1-745 of human Tie2 fused to a His·Tag™ sequence

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽140-45kDa Tie2 protein.

Content And Storage:
−20°C

Isotype:
IgG1

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Invitrogen

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Antigen:
CD20

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Monoclonal

Conjugate:
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Host Species:
Mouse

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Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2H7

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Immunogen:
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Regulatory Status:
RUO

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Content And Storage:
4° C, store in dark, DO NOT FREEZE!

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Conjugate:
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Host Species:
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Primary or Secondary:
__

Target Species:
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Form:
__

Applications:
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Clone:
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Formulation:
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2 mL Beads and BuffersStore at 2°C to 8°C.

Isotype:
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Fischer Scientific

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Classification:
Monoclonal

Conjugate:
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Host Species:
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Primary or Secondary:
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Target Species:
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Form:
Liquid

Applications:
Flow Cytometry

Clone:
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Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Immunogen:
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Regulatory Status:
RUO

Test Specificity:
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
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