62-163-182
CD163 Monoclonal Antibody (TNKUPJ), Super Bright™ 436, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 62-163-182-Each-of-1 | In Stock | ₹ 36,619.68 |
62-163-182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,619.68
GST (18%): ₹ 6,591.542
Total Price: ₹ 43,211.222
Antigen
CD163
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q2VLH6
Gene Symbols
CD163
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
93671
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
TNKUPJ
Conjugate
Super Bright 436
Gene
CD163
Gene Alias
CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163
Host Species
Rat
Quantity
100μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- This TNKUPJ monoclonal antibody recognizes mouse CD163
- CD163 is a 130kDa surface receptor expressed by certain subsets of tissue macrophages, including splenic red pulp macrophages, Kupffer cells, intestinal lamina propria macrophages and a small fractio CD163 (M130 antigen, Ber-Mac3, Ki-M8, SM4) is a 130 kDa membrane glycoprotein, a member of the scavenger receptor cysteine-rich superfamily, and a receptor for the hemoglobin-haptoglobin complex
- CD163 protects tissues from free hemoglobin-mediated oxidative damage, and may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme
- CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation
- Specifically, CD163 is present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal centers of lymphoid follicles, interdigitating reticulum cells and Langerhan's cells
- CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes
- CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone
- Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant
- CD163 binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner, and exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP1S phenotype
- Further, CD163 also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.
Compare Similar Items
Show Difference
Antigen: CD163
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q2VLH6
Gene Symbols: CD163
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 93671
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TNKUPJ
Conjugate: Super Bright 436
Gene: CD163
Gene Alias: CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163
Host Species: Rat
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD163
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q2VLH6
Gene Symbols:
CD163
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
93671
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TNKUPJ
Conjugate:
Super Bright 436
Gene:
CD163
Gene Alias:
CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163
Host Species:
Rat
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD169 (Siglec-1)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9BZZ2
Gene Symbols: SIGLEC1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6614
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 7-239
Conjugate: Super Bright 436
Gene: SIGLEC1
Gene Alias: Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD169 (Siglec-1)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9BZZ2
Gene Symbols:
SIGLEC1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6614
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
7-239
Conjugate:
Super Bright 436
Gene:
SIGLEC1
Gene Alias:
Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD172a (SIRP alpha)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P97797
Gene Symbols: SIRPA
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19261
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: P84
Conjugate: Super Bright 436
Gene: SIRPA
Gene Alias: AI835480, Bit, brain Ig-like molecule with tyrosine-based activation motifs, Brain immunoglobulin like protein with tyrosine - based activation motifs, brain immunological-like with tyrosine-based motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD172, CD172 alpha, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, macrophage fusion receptor, Macrophage membrane protein MFP150, MFR, mSIRP-alpha1, Myd1, MYD-1, myD-1 antigen, p84, Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1), protein tyrosine phosphatase, non-receptor type substrate 1, Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1), Ptpns1, SHP substrate 1, SHP-1, SHPS1, SHPS-1, signal regulatory protein alpha, signal-regulatory protein alpha, signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP, Sirpa, SIRPalpha, Sirp-alpha-1, SIRPalpha2, Sirp-alpha-2, Sirp-alpha-3, swc3, swine workshop cluster 3 antigen, swine workshop cluster 3 antigen precursor, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor type substrate 1
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD172a (SIRP alpha)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P97797
Gene Symbols:
SIRPA
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19261
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
P84
Conjugate:
Super Bright 436
Gene:
SIRPA
Gene Alias:
AI835480, Bit, brain Ig-like molecule with tyrosine-based activation motifs, Brain immunoglobulin like protein with tyrosine - based activation motifs, brain immunological-like with tyrosine-based motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD172, CD172 alpha, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, macrophage fusion receptor, Macrophage membrane protein MFP150, MFR, mSIRP-alpha1, Myd1, MYD-1, myD-1 antigen, p84, Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1), protein tyrosine phosphatase, non-receptor type substrate 1, Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1), Ptpns1, SHP substrate 1, SHP-1, SHPS1, SHPS-1, signal regulatory protein alpha, signal-regulatory protein alpha, signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP, Sirpa, SIRPalpha, Sirp-alpha-1, SIRPalpha2, Sirp-alpha-2, Sirp-alpha-3, swc3, swine workshop cluster 3 antigen, swine workshop cluster 3 antigen precursor, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor type substrate 1
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD172a (SIRP alpha)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P97797
Gene Symbols: SIRPA
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19261
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: P84
Conjugate: Super Bright 436
Gene: SIRPA
Gene Alias: AI835480, Bit, brain Ig-like molecule with tyrosine-based activation motifs, Brain immunoglobulin like protein with tyrosine - based activation motifs, brain immunological-like with tyrosine-based motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD172, CD172 alpha, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, macrophage fusion receptor, Macrophage membrane protein MFP150, MFR, mSIRP-alpha1, Myd1, MYD-1, myD-1 antigen, p84, Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1), protein tyrosine phosphatase, non-receptor type substrate 1, Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1), Ptpns1, SHP substrate 1, SHP-1, SHPS1, SHPS-1, signal regulatory protein alpha, signal-regulatory protein alpha, signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP, Sirpa, SIRPalpha, Sirp-alpha-1, SIRPalpha2, Sirp-alpha-2, Sirp-alpha-3, swc3, swine workshop cluster 3 antigen, swine workshop cluster 3 antigen precursor, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor type substrate 1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD172a (SIRP alpha)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P97797
Gene Symbols:
SIRPA
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19261
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
P84
Conjugate:
Super Bright 436
Gene:
SIRPA
Gene Alias:
AI835480, Bit, brain Ig-like molecule with tyrosine-based activation motifs, Brain immunoglobulin like protein with tyrosine - based activation motifs, brain immunological-like with tyrosine-based motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD172, CD172 alpha, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, macrophage fusion receptor, Macrophage membrane protein MFP150, MFR, mSIRP-alpha1, Myd1, MYD-1, myD-1 antigen, p84, Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1), protein tyrosine phosphatase, non-receptor type substrate 1, Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1), Ptpns1, SHP substrate 1, SHP-1, SHPS1, SHPS-1, signal regulatory protein alpha, signal-regulatory protein alpha, signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP, Sirpa, SIRPalpha, Sirp-alpha-1, SIRPalpha2, Sirp-alpha-2, Sirp-alpha-3, swc3, swine workshop cluster 3 antigen, swine workshop cluster 3 antigen precursor, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor type substrate 1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ