70-276-6

Optineurin Recombinant Rabbit Monoclonal Antibody (22H12L20), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 70-276-6-Each-of-1 In Stock ₹ 42,780.00

70-276-6 - Each of 1

₹ 42,780.00

In Stock

Quantity

1

Base Price: ₹ 42,780.00

GST (18%): ₹ 7,700.40

Total Price: ₹ 50,480.40

Antigen

Optineurin

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

Q8K3K8, Q8R5M4, Q96CV9

Gene Symbols

OPTN

Immunogen

Peptides corresponding to human Optineurin [1) aa171-aa186, 2) aa27-aa42]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

22H12L20

Conjugate

Unconjugated

Gene

OPTN

Gene Alias

14.7K-interacting protein 2; 4930441O07Rik; Ag9 C5; ALS12; E3-14.7K-interacting protein; FIP 2; FIP2; FIP-2; FIP-2-like protein; GLC1E; HIP 7; HIP7; HIP-7; Huntingtin interacting protein L; huntingtin yeast partner L; Huntingtin-interacting protein 7; huntingtin-interacting protein L; HYPL; NEMO-related protein; NRP; Optic neuropathy-inducing protein; optineurin; Optn; TFIIIA IntP; TFIIIA-IntP; transcription factor IIIA-interacting protein; transcrption factor IIIA-interacting protein; tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Uban

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10133, 246294, 71648

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Horse, cat
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • This gene encodes the coiled-coil containing protein optineurin
  • Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma
  • Optineurin interacts with adenovirus E3-14
  • 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction
  • Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins
  • Alternative splicing results in multiple transcript variants encoding the same protein.

Compare Similar Items

Show Difference

Img

Invitrogen

70-276-6

--


Antigen:
Optineurin

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q8K3K8, Q8R5M4, Q96CV9

Gene Symbols:
OPTN

Immunogen:
Peptides corresponding to human Optineurin [1) aa171-aa186, 2) aa27-aa42]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
22H12L20

Conjugate:
Unconjugated

Gene:
OPTN

Gene Alias:
14.7K-interacting protein 2; 4930441O07Rik; Ag9 C5; ALS12; E3-14.7K-interacting protein; FIP 2; FIP2; FIP-2; FIP-2-like protein; GLC1E; HIP 7; HIP7; HIP-7; Huntingtin interacting protein L; huntingtin yeast partner L; Huntingtin-interacting protein 7; huntingtin-interacting protein L; HYPL; NEMO-related protein; NRP; Optic neuropathy-inducing protein; optineurin; Optn; TFIIIA IntP; TFIIIA-IntP; transcription factor IIIA-interacting protein; transcrption factor IIIA-interacting protein; tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Uban

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10133, 246294, 71648

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-276-8

--


Antigen:
MFN2

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O95140, Q80U63

Gene Symbols:
MFN2

Immunogen:
Peptides corresponding to human Mitofusin 2 [1) aa391-aa410 2) aa742-aa757]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
7H42L13

Conjugate:
Unconjugated

Gene:
MFN2

Gene Alias:
CMT2A; CMT2A2; CPRP 1; CPRP1; D630023P19Rik; Fzo; HMSN6A; HSG; HSG protein; hyperplasia suppressor; hypertension related protein 1; hypertension-related protein; hypertension-related protein 1; Kiaa0214; LOW QUALITY PROTEIN: mitofusin-2; Marf; MFN 2; MFN2; mg:cb01g09; Mitochondrial assembly regulatory factor; mitochondrial transmembrane GTPase FZO1A; mitofusin 2; Mitofusin2; mitofusin-2; si:dkeyp-104h9.2; Transmembrane GTPase MFN2; wu:fb79a11

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
170731, 9927

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-277-0

--


Antigen:
LIMP2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O35114, P27615, Q14108

Gene Symbols:
SCARB2

Immunogen:
Protein corresponding to human LIMP2 [aa35-aa430]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
12H5L1

Conjugate:
Unconjugated

Gene:
SCARB2

Gene Alias:
85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AMRF; CD 36; CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 2; CD36 molecule; Cd36l2; EPM4; HLGP85; I79_021583; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; Lysosome membrane protein 2; lysosome membrane protein II; MLGP85; Scarb2; Scavenger receptor class B member 2; scavenger receptor class B, member 2; sCD 36; sCD36; soluble CD 36; soluble CD36; SR-B2; SR-BII

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
117106, 12492, 950

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

70-277-6

--


Antigen:
SPG11

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q96JI7

Gene Symbols:
SPG11

Immunogen:
Peptide corresponding to human SPG11 (aa873-aa892)

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
2H25L11

Conjugate:
Unconjugated

Gene:
SPG11

Gene Alias:
6030465E24Rik; A330015I11; ALS5; C530005A01Rik; CMT2X; Colorectal carcinoma-associated protein; KIAA1840; RGD1562529; spastic paraplegia 11; spastic paraplegia 11 (autosomal recessive); spastic paraplegia 11 protein; Spastic paraplegia 11 protein homolog; spatacsin; Spg11

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
80208

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid