7068330

CX3CR1 Monoclonal Antibody (2A9-1), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CX3CR1

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28

Gene Symbols

CX3CR1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

CX3CR1

Clone

2A9-1

Applications

Flow Cytometry

Conjugate

PE

Host Species

Rat

Target Species

Human

Gene Accession No.

P49238

Gene ID (Entrez)

1524

Isotype

IgG2b κ

Purification Method

Affinity chromatography

Product Type

Antibody

Related Products

Img

Fischer Scientific

7068330

Rat Monoclonal Antibody...

Img

Fischer Scientific

7068107

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7068944

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7069393

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7068110

Rat Monoclonal Antibody...

Img

Fischer Scientific

7068109

Rat Monoclonal Antibody...

Img

Fischer Scientific

7068943

Armenian Hamster Monoclonal Antibod...

Img

Fischer Scientific

7068720

Armenian Hamster Monoclonal Antibod...

Description

  • Description: This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family
  • CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g
  • CD8+, CD4+, and gamma/delta), and monocytes
  • In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia
  • Little to no CX3CR1 surface expression can be detected on B cells and granulocytes
  • Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes
  • The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B
  • Applications Reported: This 2A9-1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 2A9-1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection
  • The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively
  • The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1
  • Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine
  • CX3CR1 mediates leukocyte migration an d adhesion
  • CX3CR1 is expressed in a variety of human tissues and cell lines.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7068330

Rat Monoclonal Antibody...


Antigen:
CX3CR1

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28

Gene Symbols:
CX3CR1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CX3CR1

Clone:
2A9-1

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P49238

Gene ID (Entrez):
1524

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7068332

Rat Monoclonal Antibody...


Antigen:
TOX

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1

Gene Symbols:
TOX

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
TOX

Clone:
TXRX10

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
O94900, Q66JW3

Gene ID (Entrez):
252838, 9760

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7068336

Mouse Monoclonal Antibody...


Antigen:
CD261 (DR4)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a

Gene Symbols:
TNFRSF10A

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
TNFRSF10A

Clone:
DJR1

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O00220

Gene ID (Entrez):
8797

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7068336

Mouse Monoclonal Antibody...


Antigen:
CD261 (DR4)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a

Gene Symbols:
TNFRSF10A

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
TNFRSF10A

Clone:
DJR1

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O00220

Gene ID (Entrez):
8797

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody