7068870

CD91 Monoclonal Antibody (A2MR-a2), PE, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD91

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

A2MR; AI316852; alpha 2-macroglobulin receptor; alpha-2-macroglobulin receptor; APOER; Apolipoprotein E receptor; APR; b2b1554Clo; CD91; FLJ16451; IGFBP3R; LDL receptor related protein 1; lipoprotein receptor-related protein; low density lipoprotein receptor-related protein 1; low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor); Low-density lipoprotein receptor-related protein 1 515 kDa subunit; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; Low-density lipoprotein receptor-related protein 1 intracellular domain; Lrp; Lrp1; LRP-1; LRP1A; LRP-515; LRP-85; LRPICD; MGC88725; Prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor

Gene Symbols

LRP1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

LRP1

Clone

A2MR-a2

Applications

Flow Cytometry

Conjugate

PE

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q07954

Gene ID (Entrez)

4035

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: The A2MR-a2 monoclonal antibody reacts with human CD91, also known as LRP-1 and alpha-2 macroglobulin receptor
  • CD91 is a 600 kDa, type 1 transmembrane protein consisting of an alpha and beta chain
  • The alpha chain interacts with multiple structurally and functionally diverse ligands and the beta chain contains 2 tyrosine phosphorylation motifs capable of interacting with adaptor and signaling proteins
  • Binding of ligands mediates ligand endocytosis and trafficking to lysosomes
  • This receptor is expressed by cells in the monocytic lineage, dendritic cells, hepatocytes, firbroblasts, adipocytes, neurons, and syncytiotrophoblast
  • CD91 is involved in cross-presenting antigens via MHC class I molecules on antigen presenting cells after endocytosis of heat shock protein-peptide complexes
  • It also plays a role in cell migration and is involved in activating signaling cascades
  • Applications Reported: This A2MR-a2 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This A2MR-a2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.06 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
  • The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells
  • In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients
  • Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.

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Antigen:
CD91

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
A2MR; AI316852; alpha 2-macroglobulin receptor; alpha-2-macroglobulin receptor; APOER; Apolipoprotein E receptor; APR; b2b1554Clo; CD91; FLJ16451; IGFBP3R; LDL receptor related protein 1; lipoprotein receptor-related protein; low density lipoprotein receptor-related protein 1; low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor); Low-density lipoprotein receptor-related protein 1 515 kDa subunit; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; Low-density lipoprotein receptor-related protein 1 intracellular domain; Lrp; Lrp1; LRP-1; LRP1A; LRP-515; LRP-85; LRPICD; MGC88725; Prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor

Gene Symbols:
LRP1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
LRP1

Clone:
A2MR-a2

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q07954

Gene ID (Entrez):
4035

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
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Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6

Gene Symbols:
FAS

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
FAS

Clone:
DX2

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Mouse

Target Species:
Canine, Human

Gene Accession No.:
P25445

Gene ID (Entrez):
355, 486469

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
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Classification:
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Form:
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Regulatory Status:
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Formulation:
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Gene Alias:
Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7

Gene Symbols:
CD101

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD101

Clone:
Moushi101

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
A8E0Y8

Gene ID (Entrez):
630146

Isotype:
IgG2a κ

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Affinity chromatography

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Antibody

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Antigen:
CD105 (Endoglin)

Concentration:
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Classification:
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Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Gene Symbols:
ENG

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
ENG

Clone:
MJ7/18

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q63961

Gene ID (Entrez):
13805

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody