7069035

CD105 (Endoglin) Monoclonal Antibody (MJ7/18), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD105 (Endoglin)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Gene Symbols

ENG

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

ENG

Clone

MJ7/18

Applications

Flow Cytometry

Conjugate

Biotin

Host Species

Rat

Target Species

Mouse

Gene Accession No.

Q63961

Gene ID (Entrez)

13805

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin
  • This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells
  • It is suggested that CD105 functions in adhesion and embryonic angiogenesis
  • Applications Reported: The MJ7/18 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: The MJ7/18 antibody has been tested by flow cytometric analysis of bEnd.3 cells and mouse splenocytes
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells
  • It exists on an O- and N-glycosylated homodimer
  • Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker
  • CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

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Img

Fischer Scientific

7069035

Rat Monoclonal Antibody...


Antigen:
CD105 (Endoglin)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Gene Symbols:
ENG

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
ENG

Clone:
MJ7/18

Applications:
Flow Cytometry

Conjugate:
Biotin

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q63961

Gene ID (Entrez):
13805

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD107a (LAMP-1)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Gene Symbols:
LAMP1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
LAMP1

Clone:
eBio1D4B (1D4B)

Applications:
Flow Cytometry

Conjugate:
Biotin

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P11438

Gene ID (Entrez):
16783

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD127

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R

Gene Symbols:
Il7r

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Il7r

Clone:
A7R34

Applications:
Flow Cytometry

Conjugate:
Biotin

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P16872

Gene ID (Entrez):
16197

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD133 (Prominin-1)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
4932416E19Rik; AC133; Antigen AC133; antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-1.s2; prominin-like 1; prominin-like protein 1; PROML1; RP41; STGD4

Gene Symbols:
PROM1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
PROM1

Clone:
13A4

Applications:
Flow Cytometry

Conjugate:
Biotin

Host Species:
Rat

Target Species:
Canine, Mouse

Gene Accession No.:
O54990

Gene ID (Entrez):
19126, 488816

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody