7069355

CD106 (VCAM-1) Monoclonal Antibody (eBioMR106 (MR106)), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD106 (VCAM-1)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B

Gene Symbols

VCAM1

Primary or Secondary

Primary

Content And Storage

4° C

Gene

VCAM1

Clone

eBioMR106 (MR106)

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Rat

Gene Accession No.

P29534

Gene ID (Entrez)

25361

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells
  • Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation
  • CD106 binds to integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin alpha4beta7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development
  • Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response
  • Applications Reported: This eBioMR106 (MR106) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistology staining of frozen tissue sections
  • Applications Tested: This eBioMR106 (MR106) antibody has been tested by flow cytometric analysis of rat bone marrow cells
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine activated endothelium
  • The protein has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases.

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Show Difference

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Fischer Scientific

7069355

Mouse Monoclonal Antibody...


Antigen:
CD106 (VCAM-1)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B

Gene Symbols:
VCAM1

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
VCAM1

Clone:
eBioMR106 (MR106)

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
P29534

Gene ID (Entrez):
25361

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7069356

Rat Monoclonal Antibody...


Antigen:
CD106 (VCAM-1)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
__

Gene Alias:
__

Gene Symbols:
__

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
__

Clone:
429

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P29533

Gene ID (Entrez):
22329

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7069361

Rat Monoclonal Antibody...


Antigen:
CD115 (c-fms)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; CSFIR; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms

Gene Symbols:
Csf1r

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Csf1r

Clone:
AFS98

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P09581

Gene ID (Entrez):
12978

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD117 (c-Kit)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Gene Symbols:
KIT

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
KIT

Clone:
2B8

Applications:
Flow Cytometry, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Mouse, Porcine

Gene Accession No.:
P05532, Q2HWD6

Gene ID (Entrez):
16590, 396810

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody