Invitrogen™ LanthaScreen™ Tb-peIF2a (pSer52) Antibody

Description

• The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis
• In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis
• For use in combination with the GFP-EIF2alpha physiological protein substrate (Cat
• No
• PV4809) to evaluate inhibitors in medium to high throughput screening applications.