7078469

CD39 Monoclonal Antibody (24DMS1), Super Bright™ 436, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD39

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64

Gene Symbols

ENTPD1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

ENTPD1

Clone

24DMS1

Applications

Flow Cytometry

Conjugate

Super Bright 436

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P55772

Gene ID (Entrez)

12495

Isotype

IgG2b κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • Description: The 24DMS1 monoclonal antibody reacts with mouse CD39, also known as NTPDaseI
  • E-NTPDases are enzymes that convert nucleoside tri- and diphosphates (NTDPs) into nucleoside monophosphate (NMP), thereby removing toxic extracellular ATP and ADP
  • CD39 is the domit member of this family in the immune system and is involved in suppression of inflammation and control of platelet activation
  • CD39 can impact expression of CD73, another E-NTPase
  •  Together, these molecules influence inflammation responses
  • CD39 is expressed on B cells, Langerhans cells and most monocytes
  • In addition, CD39 is found on a subset of CD4+ T cells that are mostly CD25+FoxP3+ T reg cells
  • T reg cells from CD39-null mice showed impaired suppressive properties in vitro and in vivo
  • Applications Reported: This 24DMS1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 24DMS1 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm
  • CD39 cell surface antigen is a 70-100kD molecule expressed on peripheral blood B cells, monocytes, T cell clones, and also weakly expressed on granulocytes
  • CD39 has intrinsic ecto-ATPase activity
  • Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.

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Fischer Scientific

7078469

Rat Monoclonal Antibody...


Antigen:
CD39

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64

Gene Symbols:
ENTPD1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
ENTPD1

Clone:
24DMS1

Applications:
Flow Cytometry

Conjugate:
Super Bright 436

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P55772

Gene ID (Entrez):
12495

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7078470

Mouse Monoclonal Antibody...


Antigen:
CD4

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Gene Symbols:
CD4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD4

Clone:
SK3 (SK-3)

Applications:
Flow Cytometry

Conjugate:
Super Bright 436

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01730

Gene ID (Entrez):
920

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7078471

Mouse Monoclonal Antibody...


Antigen:
CD4

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Gene Symbols:
CD4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD4

Clone:
SK3 (SK-3)

Applications:
Flow Cytometry

Conjugate:
Super Bright 600

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01730

Gene ID (Entrez):
920

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7078472

Rat Monoclonal Antibody...


Antigen:
CD4

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Gene Symbols:
CD4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD4

Clone:
RM4-5

Applications:
Flow Cytometry

Conjugate:
Super Bright 600

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06332

Gene ID (Entrez):
12504

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody