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7078778

Cytokeratin 10 Antibody (KRT10/844 + KRT10/1275) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Cytokeratin 10

Concentration

1 mg/mL

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cytoskeleton Markers

Formulation

PBS with No Preservative

Gene ID (Entrez)

3858

Immunogen

Recombinant human KRT10 protein

Primary or Secondary

Primary

Content And Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Molecular Weight of Antigen

56.5 kDa

Clone

KRT10/844 + KRT10/1275

Dilution

Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.1 - 0.2 ug/ml, CyTOF-ready

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Alias

BCIE, BIE, CK10, CK-10, cytokeratin 10, Cytokeratin-10, EHK, K10keratosis palmaris et plantaris, keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), keratin, type I cytoskeletal 10, keratin-10, KPP

Gene Symbols

KRT10

Isotype

IgG1 κ

Purification Method

Protein A or G purified

Test Specificity

This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Description

  • Cytokeratin 10 Monoclonal specifically detects Cytokeratin 10 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

7078778

Mouse Monoclonal Antibody...

Antigen:
Cytokeratin 10
Concentration:
1 mg/mL
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeleton Markers
Formulation:
PBS with No Preservative
Gene ID (Entrez):
3858
Immunogen:
Recombinant human KRT10 protein
Primary or Secondary:
Primary
Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
56.5 kDa
Clone:
KRT10/844 + KRT10/1275
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.1 - 0.2 ug/ml, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
BCIE, BIE, CK10, CK-10, cytokeratin 10, Cytokeratin-10, EHK, K10keratosis palmaris et plantaris, keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), keratin, type I cytoskeletal 10, keratin-10, KPP
Gene Symbols:
KRT10
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Img

Fischer Scientific

7078780

Mouse Monoclonal Antibody...

Antigen:
Cytokeratin 15
Concentration:
1 mg/mL
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeleton Markers
Formulation:
PBS with No Preservative
Gene ID (Entrez):
3866
Immunogen:
Recombinant human KRT15 protein
Primary or Secondary:
Primary
Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.
Molecular Weight of Antigen:
52 kDa
Clone:
KRT15/1699
Dilution:
Western Blot 0.5 - 1 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5-1 ug/ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Rat, Bovine
Gene Alias:
CK15, CK-15, cytokeratin 15, cytokeratin-15, K15keratin-15, basic, K1CO, keratin 15, keratin, type I cytoskeletal 15, Keratin-15, keratin-15, beta, KRTB, type I cytoskeletal 15
Gene Symbols:
KRT15
Isotype:
IgG2a κ
Purification Method:
Protein A or G purified
Test Specificity:
__

Img

Fischer Scientific

7078781

Mouse Monoclonal Antibody...

Antigen:
Cytokeratin 15
Concentration:
0.2 mg/mL
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeleton Markers
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez):
3866
Immunogen:
A 17 amino acids synthetic peptide from the C- terminal of Human Cytokeratin 15 (exact sequence is proprietary)
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Molecular Weight of Antigen:
52 kDa
Clone:
LHK15
Dilution:
Western Blot 0.5 - 1 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1 ug/ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, SDS-Page
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Rat, Bovine
Gene Alias:
CK15, CK-15, cytokeratin 15, cytokeratin-15, K15keratin-15, basic, K1CO, keratin 15, keratin, type I cytoskeletal 15, Keratin-15, keratin-15, beta, KRTB, type I cytoskeletal 15
Gene Symbols:
KRT15
Isotype:
IgG2a κ
Purification Method:
Protein A or G purified
Test Specificity:
__

Img

Fischer Scientific

7078783

Mouse Monoclonal Antibody...

Antigen:
Cytokeratin 15
Concentration:
0.2 mg/mL
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeleton Markers
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez):
3866
Immunogen:
A 17 amino acids synthetic peptide from the C- terminal of Human Cytokeratin 15
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Molecular Weight of Antigen:
52 kDa
Clone:
SPM190
Dilution:
Western Blot 0.5 - 1 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1 ug/ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human, Rat, Bovine
Gene Alias:
CK15, CK-15, cytokeratin 15, cytokeratin-15, K15keratin-15, basic, K1CO, keratin 15, keratin, type I cytoskeletal 15, Keratin-15, keratin-15, beta, KRTB, type I cytoskeletal 15
Gene Symbols:
KRT15
Isotype:
IgG2a κ
Purification Method:
Protein A or G purified
Test Specificity:
__