7078893
Filaggrin Antibody (SPM181), Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Filaggrin
Concentration
0.2 mg/mL
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Host Species
Mouse
Research Discipline
Cytoskeleton Markers
Formulation
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez)
2312
Immunogen
Recombinant human Filaggrin protein
Primary or Secondary
Primary
Content And Storage
Store at 4C.
Clone
SPM181
Dilution
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Target Species
Human
Gene Alias
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols
FLG
Isotype
IgG1 κ
Purification Method
Protein A or G purified
Test Specificity
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Description
- Filaggrin Monoclonal specifically detects Filaggrin in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Filaggrin
Concentration: 0.2 mg/mL
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cytoskeleton Markers
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez): 2312
Immunogen: Recombinant human Filaggrin protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Clone: SPM181
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols: FLG
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Antigen:
Filaggrin
Concentration:
0.2 mg/mL
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeleton Markers
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez):
2312
Immunogen:
Recombinant human Filaggrin protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Clone:
SPM181
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols:
FLG
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Antigen: Filaggrin
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cytoskeleton Markers
Formulation: PBS with No Preservative
Gene ID (Entrez): 2312
Immunogen: Recombinant human Filaggrin protein
Primary or Secondary: Primary
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Clone: SPM181
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols: FLG
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Antigen:
Filaggrin
Concentration:
1 mg/mL
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeleton Markers
Formulation:
PBS with No Preservative
Gene ID (Entrez):
2312
Immunogen:
Recombinant human Filaggrin protein
Primary or Secondary:
Primary
Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.
Clone:
SPM181
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols:
FLG
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Antigen: Filaggrin
Concentration: 1 mg/mL
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: Cytoskeleton Markers
Formulation: PBS with No Preservative
Gene ID (Entrez): 2312
Immunogen: Recombinant human Filaggrin protein
Primary or Secondary: Primary
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Clone: SPM181
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols: FLG
Isotype: IgG1 κ
Purification Method: Protein A or G purified
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Antigen:
Filaggrin
Concentration:
1 mg/mL
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
Cytoskeleton Markers
Formulation:
PBS with No Preservative
Gene ID (Entrez):
2312
Immunogen:
Recombinant human Filaggrin protein
Primary or Secondary:
Primary
Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.
Clone:
SPM181
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols:
FLG
Isotype:
IgG1 κ
Purification Method:
Protein A or G purified
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Antigen: FSH R
Concentration: 0.2 mg/mL
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Research Discipline: GPCR
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez): 2492
Immunogen: Recombinant human full-length FSHR protein
Primary or Secondary: Primary
Content And Storage: Store at 4C.
Clone: FSHR/1400
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Target Species: Human
Gene Alias: follicle stimulating hormone receptor, follicle-stimulating hormone receptor, Follitropin receptor, FSH receptor, FSH-R, LGR1FSHRO, MGC141667, MGC141668, ODG1
Gene Symbols: FSHR
Isotype: IgG1
Purification Method: Protein A or G purified
Test Specificity: __
Antigen:
FSH R
Concentration:
0.2 mg/mL
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Research Discipline:
GPCR
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene ID (Entrez):
2492
Immunogen:
Recombinant human full-length FSHR protein
Primary or Secondary:
Primary
Content And Storage:
Store at 4C.
Clone:
FSHR/1400
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Target Species:
Human
Gene Alias:
follicle stimulating hormone receptor, follicle-stimulating hormone receptor, Follitropin receptor, FSH receptor, FSH-R, LGR1FSHRO, MGC141667, MGC141668, ODG1
Gene Symbols:
FSHR
Isotype:
IgG1
Purification Method:
Protein A or G purified
Test Specificity:
__