Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Perilipin-2/ADFP
0.2 mg/mL
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Unconjugated
Mouse
Cancer, Hypoxia, Lipid and Metabolism, Lipid Droplets, Signal Transduction
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
123
Recombinant human Adipophilin protein fragment (aa249-376) (exact sequence is proprietary)
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
48 kDa
ADFP/1494
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin 2-4 ug/ml, Immunofluorescence 0.5-1.0 ug/ml
Monoclonal
Purified
RUO
Human
ADFP, Adipophilin, Adipose differentiation-related proteinadipophilin, ADRP, MGC10598, perilipin 2, perilipin-2
PLIN2
IgG2b κ
Protein A or G purified
Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.