Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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TfR (Transferrin R)
1 mg/mL
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers
PBS with No Preservative
7037
Recombinant human extracellular TFRC protein fragment (aa94-212) (exact sequence is proprietary)
Primary
Store at -20 to -80C. Avoid freeze-thaw cycles.
TFRC/1818
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, ELISA 2 - 4 ug/ml, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready
Monoclonal
Purified
RUO
Human
CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr
TFRC
IgG2b κ
Protein A or G purified
It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.