7090012

CD32b Monoclonal Antibody (AT130-2), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD32b

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

AI528646; CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CD32B; CDw32; F630109E10Rik; Fc fragment of IgG receptor IIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); fc gamma receptor IIB; Fc gamma RIIb; Fc receptor, IgG, low affinity IIb; Fc[g]RII; FCG2; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma-RII; fc-gamma-RIIa; FcgammaRIIB; fc-gamma-RIIb; FcgammaRIIB2; FcGR; Fcgr2; Fcgr2a; FCGR2A1; FCGR2B; FcgRII; Fcr-2; Fcr-3; fcRII; fcRII-a; fcRII-b; FGFR2B; IGFR2; IgG Fc receptor II beta; igG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; LyM-1; Ly-m20; Lymphocyte antigen 17

Gene Symbols

FCGR2B

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

FCGR2B

Clone

AT130-2

Applications

Flow Cytometry

Conjugate

APC

Host Species

Mouse

Target Species

Mouse

Gene Accession No.

P08101

Gene ID (Entrez)

14130

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • Description: The monoclonal antibody AT130-2 reacts with mouse CD32b, also known as Fc-gamma receptor IIb
  • CD32b is the only inhibitory member of the Fc-gamma receptor family
  • Immune complex engagement of CD32b results in the phosphorylation of its intracellular ITIM motif
  • This engagement serves to attenuate B cell receptor (BCR) signaling and other activating signals, reduces proliferation, reduces antibody production, and may also deliver apoptotic signals
  • CD32b is the only Fc-gamma receptor expressed by B cells
  • CD32b is also expressed on monocytes, dendritic cells, neutrophils, eosinophils and basophils, as well as B cell progenitors and plasma cells
  • AT130-2 has been reported to have agonist activity
  • Applications Reported: This AT130-2 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This AT130-2 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells
  • The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes
  • Alternative splicing results in multiple transcript variants.

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7090012

Mouse Monoclonal Antibody...


Antigen:
CD32b

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AI528646; CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CD32B; CDw32; F630109E10Rik; Fc fragment of IgG receptor IIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); fc gamma receptor IIB; Fc gamma RIIb; Fc receptor, IgG, low affinity IIb; Fc[g]RII; FCG2; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma-RII; fc-gamma-RIIa; FcgammaRIIB; fc-gamma-RIIb; FcgammaRIIB2; FcGR; Fcgr2; Fcgr2a; FCGR2A1; FCGR2B; FcgRII; Fcr-2; Fcr-3; fcRII; fcRII-a; fcRII-b; FGFR2B; IGFR2; IgG Fc receptor II beta; igG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; LyM-1; Ly-m20; Lymphocyte antigen 17

Gene Symbols:
FCGR2B

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
FCGR2B

Clone:
AT130-2

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Mouse

Gene Accession No.:
P08101

Gene ID (Entrez):
14130

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7090013

Mouse Monoclonal Antibody...


Antigen:
CD32

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD32; CD32 receptor 2; CD32 receptor 2a; CD32A; CD32B; CD32C; CDW32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc (gene/pseudogene); Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor II; Fc gamma receptor IIa; Fc gamma receptor IIb; Fc gamma receptor IIC; Fc gamma RIIb; FCG2; Fc-gamma receptor II; fc-gamma RII; Fc-gamma RII-a; fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIa; Fc-gamma-RIIb; fc-gamma-RIIc; Fc-gamma-RII-D; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; fcRII; fcRII-a; fcRII-b; FCRIIC; FGFR2B; IGFR2; IgG Fc fragment receptor; IgG Fc gamma receptor II; igG Fc receptor II; IgG Fc receptor II-a; igG Fc receptor II-b; IgG Fc receptor II-c; Immunoglobulin G Fc receptor II; immunoglobulin G Fc receptor II-c; low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-a; low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; MGC23887; MGC30032; RP11-5K23.6; soluble receptor; boFcRII-2

Gene Symbols:
FCGR2A, FCGR2B, FCGR2C

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
__

Clone:
6C4 (CD32)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P12318, P31994, P31995

Gene ID (Entrez):
2212, 2213, 9103

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7090014

Mouse Monoclonal Antibody...


Antigen:
CD33

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3

Gene Symbols:
CD33

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD33

Clone:
WM-53 (WM53)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P20138

Gene ID (Entrez):
945

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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7090015

Mouse Monoclonal Antibody...


Antigen:
CD34

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1; AU040960; CD34; CD34 antigen; CD34 molecule; CDC34; cell division cycle 34; cell division cycle 34 homolog; cluster designation 34; cluster of differentiation antigen 34; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell marker CD34; Mucosialin; RP11-328D5.2; sialomucin protein; type 1 transmembrane protein; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Gene Symbols:
Cd34

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Cd34

Clone:
4H11

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P28906

Gene ID (Entrez):
947

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody