7090263
IRF8 Monoclonal Antibody (V3GYWCH), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
IRF8
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Alias
AI893568; H-ICSBP; Icsbp; Icsbp1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; Interferon consensus sequence-binding protein; Interferon regulatory factor 8; Irf8; IRF-8; Myls; transcription factor ICSBP
Gene Symbols
Irf8
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
Irf8
Clone
V3GYWCH
Applications
Flow Cytometry
Conjugate
APC
Host Species
Mouse
Target Species
Human, Mouse
Gene Accession No.
P23611, Q02556
Gene ID (Entrez)
15900, 3394
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Description
- Description: The V3GYWCH monoclonal antibody reacts with human and mouse interferon regulatory factor 8 (IRF8; ICSBP)
- IRF8 is a 50 kDa transcription factor that plays a critical role in the development of dendritic cells (DC)
- Specifically, IRF8 is essential in the development and differentiation of plasmacytoid DC (pDC) and CD8a+ DC
- IRF8-/- mice are deficient in both pDC and CD8a+ DC populations
- CD8a- DC are present in normal numbers in IRF8-/- mice but fail to mature upon Toll-like receptor signaling and are functionally impaired in response to in vivo microbial stimulation
- IRF8 deficiency does not affect the frequency or viability of DC precursors and as a result retroviral IRF8 transduction restores pDC development from DC progenitors in IRF8-/- mice
- Applications Reported: This V3GYWCH antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This V3GYWCH antibody has been tested by intracellular staining and flow cytometric analysis of normal human peripheral blood cells using the Foxp3/Transcription Factor Staining Buffer Set (cat
- 00-5523) and protocol
- Please refer to Best Protocols: Protocol B: One-step protocol: intracellular (nuclear) proteins located under the Resources Tab online
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- IRF8 Monoclonal antibody specifically detects IRF8 in Human, Mouse samples
- It is validated for Flow Cytometry.
Compare Similar Items
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Antigen: IRF8
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: AI893568; H-ICSBP; Icsbp; Icsbp1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; Interferon consensus sequence-binding protein; Interferon regulatory factor 8; Irf8; IRF-8; Myls; transcription factor ICSBP
Gene Symbols: Irf8
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Irf8
Clone: V3GYWCH
Applications: Flow Cytometry
Conjugate: APC
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: P23611, Q02556
Gene ID (Entrez): 15900, 3394
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
IRF8
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
AI893568; H-ICSBP; Icsbp; Icsbp1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; Interferon consensus sequence-binding protein; Interferon regulatory factor 8; Irf8; IRF-8; Myls; transcription factor ICSBP
Gene Symbols:
Irf8
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Irf8
Clone:
V3GYWCH
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
P23611, Q02556
Gene ID (Entrez):
15900, 3394
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: BCL6
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias: B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; Bcl6; Bcl-6; BCL6 transcription repressor; BCL6A; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S; ZNF51
Gene Symbols: BCL6
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: BCL6
Clone: BCL-UP
Applications: Flow Cytometry
Conjugate: APC
Host Species: Mouse
Target Species: Human
Gene Accession No.: P41182
Gene ID (Entrez): 604
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
BCL6
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; Bcl6; Bcl-6; BCL6 transcription repressor; BCL6A; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S; ZNF51
Gene Symbols:
BCL6
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
BCL6
Clone:
BCL-UP
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P41182
Gene ID (Entrez):
604
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: HLA-DQ
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias: BoLA-DQA; BOLA-DQA1; BOLA-DQA2; BOLA-DQA2 protein; BOLA-DQA3; BOLA-DQA5; BOLA-DQB; CELIAC1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatability complex class II; major histocompatibility complex, class II, DQ alpha 1 precursor; major histocompatibility complex, class II, DQ alpha 2; major histocompatibility complex, class II, DQ alpha 5; major histocompatibility complex, class II, DQ alpha, type 1; major histocompatibility complex, class II, DQ alpha, type 3; major histocompatibility complex, class II, DQ beta; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II antigen precursor; MHC class II DQ beta chain; MHC class II DQA; MHC class II DQA precursor; MHC class II DQA1 precursor; MHC class II DQA2 (BoLA-DQA2); MHC class II DQA2 precursor; MHC class II DQB precursor; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; similar to MHC class II DQA2 (BoLA-DQA2); Unknown (protein for MGC:127488); Unknown (protein for MGC:137100)
Gene Symbols: HLA-DQB1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: HLA-DQB1
Clone: SK10
Applications: Flow Cytometry
Conjugate: APC
Host Species: Mouse
Target Species: Human
Gene Accession No.: P01920
Gene ID (Entrez): 3119
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
HLA-DQ
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
BoLA-DQA; BOLA-DQA1; BOLA-DQA2; BOLA-DQA2 protein; BOLA-DQA3; BOLA-DQA5; BOLA-DQB; CELIAC1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatability complex class II; major histocompatibility complex, class II, DQ alpha 1 precursor; major histocompatibility complex, class II, DQ alpha 2; major histocompatibility complex, class II, DQ alpha 5; major histocompatibility complex, class II, DQ alpha, type 1; major histocompatibility complex, class II, DQ alpha, type 3; major histocompatibility complex, class II, DQ beta; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II antigen precursor; MHC class II DQ beta chain; MHC class II DQA; MHC class II DQA precursor; MHC class II DQA1 precursor; MHC class II DQA2 (BoLA-DQA2); MHC class II DQA2 precursor; MHC class II DQB precursor; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; similar to MHC class II DQA2 (BoLA-DQA2); Unknown (protein for MGC:127488); Unknown (protein for MGC:137100)
Gene Symbols:
HLA-DQB1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
HLA-DQB1
Clone:
SK10
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P01920
Gene ID (Entrez):
3119
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD278 (ICOS)
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Gene Symbols: ICOS
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: ICOS
Clone: ISA-3
Applications: Flow Cytometry
Conjugate: APC
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q9Y6W8
Gene ID (Entrez): 29851
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD278 (ICOS)
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Gene Symbols:
ICOS
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
ICOS
Clone:
ISA-3
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q9Y6W8
Gene ID (Entrez):
29851
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody