7090545

FOXP3 Monoclonal Antibody (PCH101), PE-Cyanine5.5, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

FOXP3

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Gene Symbols

Foxp3

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Foxp3

Clone

PCH101

Applications

Flow Cytometry

Conjugate

PE-Cyanine5.5

Host Species

Rat

Target Species

Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey

Gene Accession No.

Q6U8D7, Q9BZS1

Gene ID (Entrez)

102120882, 50943, 574303, 740909

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: eBioscience offers a panel of monoclonal antibodies to different epitopes of human Foxp3, providing useful tools for investigating the complete expression pattern of Foxp3 at the protein level, and discerning the precise subsets of Foxp3^+ cells
  • The PCH101 antibody reacts with the amino terminus of human foxp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2; cross reactivity of this antibody to other proteins has not been determined
  • Foxp3, a 49-55 kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in 'scurfy' (sf) mice
  • Constitutive high expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells
  • Intracellular staining of human peripheral blood mononuclear cells (PBMCs) with PCH101 antibody using the anti-human Foxp3 Staining Set and protocol reveals approximately 0.5-4% of lymphocytes staining, with the majority of staining occurring in the CD25^bright population
  • This is subject to donor variability
  • PCH101 crossreacts with rhesus, chimpanzee and cynomolgus
  • We recommend the use of CD4 (OKT4, cat
  • 11-0048, or RPA-T4, cat
  • 11-0049, depending on the species) and CD25 (BC96, cat
  • 17-0259)
  • Applications Reported: This PCH101 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • FOXP3 Monoclonal antibody specifically detects FOXP3 in Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey samples
  • It is validated for Flow Cytometry.

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Show Difference

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7090545

Rat Monoclonal Antibody...


Antigen:
FOXP3

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Gene Symbols:
Foxp3

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Foxp3

Clone:
PCH101

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine5.5

Host Species:
Rat

Target Species:
Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey

Gene Accession No.:
Q6U8D7, Q9BZS1

Gene ID (Entrez):
102120882, 50943, 574303, 740909

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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7090546

Rat Monoclonal Antibody...


Antigen:
FOXP3

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Gene Symbols:
Foxp3

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Foxp3

Clone:
FJK-16s

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine5.5

Host Species:
Rat

Target Species:
Bovine, Canine, Feline, Mouse, Porcine, Rat

Gene Accession No.:
Q99JB6

Gene ID (Entrez):
100037405, 20371, 317382, 444998, 491876, 506053

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
Ly-6G/Ly-6C

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN

Gene Symbols:
Ly6c1, Ly6c2, Ly6g

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
__

Clone:
RB6-8C5

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine5.5

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P0CW02, P0CW03, P35461

Gene ID (Entrez):
100041546, 17067, 546644

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD4

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Gene Symbols:
CD4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD4

Clone:
RM4-5

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen)

Conjugate:
eFluor 570

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06332

Gene ID (Entrez):
12504

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody