7090785

CD195 (CCR5) Monoclonal Antibody (HM-CCR5 (7A4)), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD195 (CCR5)

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Gene Symbols

CCR5

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

CCR5

Clone

HM-CCR5 (7A4)

Applications

Flow Cytometry

Conjugate

PerCP-eFluor 710

Host Species

Armenian Hamster

Target Species

Mouse

Gene Accession No.

P51682

Gene ID (Entrez)

12774

Isotype

IgG

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • Description: CCR5 is the major co-receptor for macrophage-tropic isolates of HIV-1
  • CCR5, also known as CD195, is a seven transmembrane chemokine receptor capable of binding RANTES, MIP-1 alpha and MIP-1 beta
  • Knockout mice show a decreased recruitment of macrophages and increased susceptibility to infection
  • Protein and mRNA has been found in macrophages from thioglycolate-treated and activated T cells
  • The HM-CCR5(7A4) monoclonal antibody binds the N terminal extracellular domain of mouse CCR5 with no crossreactivity to human CCR5
  • Applications Reported: This HM-CCR5 (7A4) antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This HM-CCR5 (7A4) antibody has been tested by flow cytometric analysis of mouse thioglycolated- induced peritoneal exudate cells
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • PerCP-eFluor™ 710 can be used in place of PE-Cy5, PE-Cy5.5 or PerCP-Cy5.5
  • PerCP-eFluor™ 710 emits at 710 nm and is excited with the blue laser (488 nm)
  • Please make sure that your instrument is capable of detecting this fluorochrome
  • CD195 (CCR5) Monoclonal antibody specifically detects CD195 (CCR5) in Mouse samples
  • It is validated for Flow Cytometry.

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7090785

Armenian Hamster Monoclonal Antibod...


Antigen:
CD195 (CCR5)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Gene Symbols:
CCR5

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CCR5

Clone:
HM-CCR5 (7A4)

Applications:
Flow Cytometry

Conjugate:
PerCP-eFluor 710

Host Species:
Armenian Hamster

Target Species:
Mouse

Gene Accession No.:
P51682

Gene ID (Entrez):
12774

Isotype:
IgG

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
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Classification:
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Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
BLR2; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; C-C chemokine receptor type 7; C-C CKR-7; C-C motif chemokine receptor 7; CC-CKR-7; CCR7; CCR-7; CD197; CDw197; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; Cmkbr7; EBI1; Ebi1h; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor

Gene Symbols:
Ccr7

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Ccr7

Clone:
3D12

Applications:
Flow Cytometry

Conjugate:
PerCP-eFluor 710

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P32248

Gene ID (Entrez):
1236

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
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Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4

Gene Symbols:
Mrc1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Mrc1

Clone:
19.2

Applications:
Flow Cytometry

Conjugate:
PerCP-eFluor 710

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P22897

Gene ID (Entrez):
4360

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
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Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Gene Symbols:
LAG3

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
LAG3

Clone:
eBioC9B7W (C9B7W)

Applications:
Flow Cytometry

Conjugate:
PerCP-eFluor 710

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q61790

Gene ID (Entrez):
16768

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody