7092386

αβ T-Cell Receptor Mouse anti-Rat, FITC, Clone: R73, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

αβ T-Cell Receptor

Concentration

0.5mg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Immunology

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Clone

R73

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Target Species

Rat

Immunogen

Rat T blasts and rat erythrocytes

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The R73 antibody reacts with the αβ T-cell Receptor (TCR) found on most peripheral T lymphocytes, intestinal intraepithelial lymphocytes, and thymocytes
  • It does not react with γδ TCR-bearing cells
  • Cross-linked R73 mAb induces T-cell differentiation and activation
  • In vivo treatment with mAb R73 can suppress immune function of peripheral αβ TCR-expressing T cells, and reduce the severity of experimental autoimmune, transplant rejection, and graft-versus-host responses.

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Antigen:
αβ T-Cell Receptor

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Monoclonal

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Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
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Clone:
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Flow Cytometry

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Regulatory Status:
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Target Species:
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Immunogen:
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Primary or Secondary:
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