CD158a Mouse anti-Human, FITC, Clone: HP-3E4, BD

Description

• Reacts wth a 58 kDa membrane glycoprotein, member of the killer-inhibitory receptor (KIR)
• The KIR family family consists of transmembrane glycoproteins of the Ig superfamily expressed on <1-8% of NK cells and a subset of T cells which are involved in recognition of MHC class I molecules on target cells and inhibit cytotoxicity
• CD158a is an antigen which recognizes HLA-C molecules (-Cw0401 and -Cw1503)
• This antibody the purified format is suitable for staining acetone-fixed, frozen tissue sections
• It was reported that this clone also cross-reacted with NKAT8 (CD158i) tranfectant cells
• This antibody is routinely tested by flow cytometric analysis
• Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.