7092447

CD184 Mouse anti-Human, PE, Clone: 12G5, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD184

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89

Clone

12G5

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

SIVmac variant CP-MAC-infected Sup-T1 cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 12G5 monoclonal antibody specifically binds to CD184, also known as CXCR4 and Fusin
  • CD184/CXCR4 is a seven-transmembrane domain, G-protein-linked, glycoprotein chemokine receptor
  • CD184 serves as a receptor for the C-X-C chemokine, SDF-1
  • It is expressed on a wide variety of hematopietic cells, vascular endothelial cells and cells of the nervous system
  • CD184 plays a variety of roles in hematopoiesis, vascularization and neural development
  • CD184 also functions as a coreceptor for infection with T-cell tropic strains of HIV-1 and as a receptor for CD4-independent infection by some HIV isolates
  • The 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.

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Fischer Scientific

7092447

Mouse Monoclonal Antibody...


Antigen:
CD184

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89

Clone:
12G5

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
SIVmac variant CP-MAC-infected Sup-T1 cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Mouse Monoclonal Antibody...


Antigen:
CD19

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
__

Clone:
HIB19

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Applications:
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Conjugate:
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Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
B4; B-lymphocyte antigen CD19; Leu-12

Clone:
SJ25C1

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human NALM1 + NALM16 cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD19

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
__

Clone:
HIB19

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.