7092521

CD3 Molecular Complex Rat anti-Mouse, PE, Clone: 17A2, BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD3 Molecular Complex

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Rat

Research Discipline

Immunology

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2b κ

Purification Method

Affinity Purified

Clone

17A2

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Target Species

Mouse

Immunogen

γδ TCR-positive T-T hybridoma D1

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes
  • Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells
  • The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11
  • This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain
  • In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells.

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Show Difference

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Fischer Scientific

7092521

Rat Monoclonal Antibody...


Antigen:
CD3 Molecular Complex

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Clone:
17A2

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Target Species:
Mouse

Immunogen:
γδ TCR-positive T-T hybridoma D1

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

7092522

Mouse Monoclonal Antibody...


Antigen:
CD3

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
__

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG1 λ

Purification Method:
Affinity Purified

Clone:
SP34-2

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 700

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Rhesus Monkey

Immunogen:
Purified Human CD3ε Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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7092523

Mouse Monoclonal Antibody...


Antigen:
CD3

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
__

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
UCHT1

Applications:
Flow Cytometry

Conjugate:
Alexa Fluor 700

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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7092524

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Antigen:
CD3

Concentration:
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Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
HIT3A

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
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Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.