7092619

CD45RO Mouse anti-Human, PE, Clone: UCHL1, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD45RO

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

Clone

UCHL1

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human IL-2-dependent T-cell line

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The UCHL1 monoclonal antibody specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen)
  • CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways
  • This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C
  • CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells
  • CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations
  • CD45RO binds to CD22.

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Show Difference

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Antigen:
CD45RO

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
UCHL1

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human IL-2-dependent T-cell line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD45RO

Applications:
Flow Cytometry

Conjugate:
PE-CF594

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
UCHL1

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human IL-2-dependent T-cell line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD47

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
MIAP301

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Not reported

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
CD47

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
MIAP301

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Not reported

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C