7092650

CD61 Mouse anti-Rat, FITC, Clone: F11, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD61

Concentration

0.5mg/mL

Classification

Monoclonal

Host Species

Mouse

Target Species

Rat

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

Integrin β3 chain

Clone

F11

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The F11 antibody reacts with the integrin β3 chain (CD61), which associates with the integrin αv chain (CD51), to form the vitronectin receptor found on endothelial cells, myeloid cells, and osteoclasts, and with the αIIb chain (CD41) on platelets and megakaryocytes
  • Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor
  • F11 mAb has been reported to block the in vitro attachment of osteoclasts to several ligands
  • Weak reactivity with human osteoclasts, megakaryocytes, and platelets has also been reported.

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Antigen:
CD61

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Rat

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
Integrin β3 chain

Clone:
F11

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD62L

Concentration:
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Classification:
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Host Species:
Rat

Target Species:
Mouse

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
Sell; L-selectin; LECAM-1; LAM-1; Lnhr; Ly-22; Ly-m22; Lyam-1

Clone:
MEL-14

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
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Host Species:
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Target Species:
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Isotype:
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Purification Method:
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Description:
P-Selectin; GMP-140; PADGEM

Clone:
AK-4

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Concentration:
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Classification:
Monoclonal

Host Species:
Mouse

Target Species:
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Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
P-Selectin; GMP-140; PADGEM

Clone:
AK-4

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.