7092716

CD95 Mouse anti-Human, PE-Cy5, Clone: DX2, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD95

Applications

Flow Cytometry

Conjugate

PE-Cyanine5

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

APO-1; FAS; TNFRSF6; APT1; ALPS1A; FAS1; FASTM; FASLG receptor

Clone

DX2

Classification

Monoclonal

Host Species

Mouse

Target Species

Baboon, Canine, Cynomolgus, Human, Porcine, Rhesus Monkey

Immunogen

Human CD95-transfected L Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The DX2 monoclonal antibody specifically binds to the human Fas antigen (also called APO-1)
  • This 45 kDa transmembrane cell surface molecule was designated as CD95 at the Fifth HLDA Workshop
  • Fas is a member of the TNF-receptor superfamily and is also known as Tumor necrosis factor receptor superfamily member 6 (TNFRSF6)
  • It is expressed on a variety of normal and neoplastic cells including activated T and B lymphocytes and some undifferentiated thymocytes
  • The Fas/CD95 antigen is a polypeptide that plays a role in the programmed sequence of events leading to cell death, termed apoptosis
  • The DX2 clone specifically reacts with murine L cells, murine L1210 leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines
  • Crosslinking CD95 with DX2 antibody delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen.

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Fischer Scientific

7092716

Mouse Monoclonal Antibody...


Antigen:
CD95

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine5

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
APO-1; FAS; TNFRSF6; APT1; ALPS1A; FAS1; FASTM; FASLG receptor

Clone:
DX2

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Canine, Cynomolgus, Human, Porcine, Rhesus Monkey

Immunogen:
Human CD95-transfected L Cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

7092717

Rat Monoclonal Antibody...


Antigen:
Cutaneous Lymphocyte Antigen

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgM κ

Purification Method:
Affinity Purified

Description:
CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG

Clone:
HECA-452

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Human, Mouse

Immunogen:
Lymphocyte-depleted Stromal Preparation of Tonsil

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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7092718

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Antigen:
CX3CR1

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.2% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28; Fractalkine Receptor

Clone:
2A9-1

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Human

Immunogen:
Human CX3CR1 Recombinant Protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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7092720

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Antigen:
CXCR5

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
__

Clone:
2G8

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CXCR5

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.