7092794
SSEA-1 Mouse, Alexa Fluor 647, Clone: MC480, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
SSEA-1
Applications
Flow Cytometry
Conjugate
Alexa Fluor 647
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
MC480
Classification
Monoclonal
Host Species
Mouse
Target Species
Human, Mouse
Isotype
IgM κ
Purification Method
Affinity Purified
Description
3-FAL, X-hapten, LeX antigen, CD15
Related Products
Description
- The MC480 monoclonal antibody reacts with S tage- S pecific Entigen-1 (SSEA-1), which is a terminal carbohydrate epitope (3-fucosyl-N-acetyllactosamine or 3-FAL) on glycoproteins and lactose series glycolipids
- SSEA-1 is related to Lewis blood group antigens and is found in a variety of embryonic and adult tissues and cancers
- As its name implies, the expression of SSEA-1 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation
- However, its expression pattern differs in the human and mouse
- In the human, SSEA-1 is not found on embryonic stem (ES) cells, embryonic inner cell mass (ICM), or teratocarcinoma (embryonal carcinoma or EC) cells
- As human EC and ES cells undergo differentiation, SSEA-1 expression is upregulated
- In the adult, the same epitope is expressed as CD15 on granulocytes and monocytes, but not lymphocytes or dendritic cells
- In the mouse, SSEA-1 is found on EC, ES, and primordial germ cells, 8-cell to blastocyst embryos, ICM, and on subpopulations of cells in the adult central nervous system, including stem cells
- In contrast to the human, SSEA-1 expression is reduced as mouse EC and ES cells undergo differentiation.
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Antigen: SSEA-1
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MC480
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Isotype: IgM κ
Purification Method: Affinity Purified
Description: 3-FAL, X-hapten, LeX antigen, CD15
Antigen:
SSEA-1
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MC480
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Isotype:
IgM κ
Purification Method:
Affinity Purified
Description:
3-FAL, X-hapten, LeX antigen, CD15
Antigen: SSEA-1
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MC480
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Isotype: IgM κ
Purification Method: Affinity Purified
Description: 3-FAL, X-hapten, LeX antigen, CD15
Antigen:
SSEA-1
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MC480
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Isotype:
IgM κ
Purification Method:
Affinity Purified
Description:
3-FAL, X-hapten, LeX antigen, CD15
Antigen: SSEA-1
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MC480
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Isotype: IgM κ
Purification Method: Affinity Purified
Description: 3-FAL, X-hapten, LeX antigen, CD15
Antigen:
SSEA-1
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MC480
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Isotype:
IgM κ
Purification Method:
Affinity Purified
Description:
3-FAL, X-hapten, LeX antigen, CD15
Antigen: SSEA-1
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: MC480
Classification: Monoclonal
Host Species: Mouse
Target Species: Human, Mouse
Isotype: IgM κ
Purification Method: Affinity Purified
Description: 3-FAL, X-hapten, LeX antigen, CD15
Antigen:
SSEA-1
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
MC480
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human, Mouse
Isotype:
IgM κ
Purification Method:
Affinity Purified
Description:
3-FAL, X-hapten, LeX antigen, CD15