71-001-5

IRAK1 Recombinant Polyclonal Antibody (19HCLC), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 71-001-5-Each In Stock ₹ 31,285.01

71-001-5 - Each

₹ 31,285.01

In Stock

Quantity

1

Base Price: ₹ 31,285.01

GST (18%): ₹ 5,631.302

Total Price: ₹ 36,916.312

Antigen

IRAK1

Classification

Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P51617, Q62406

Gene Symbols

Irak1

Immunogen

proprietary

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

19HCLC

Conjugate

Unconjugated

Gene

Irak1

Gene Alias

AA408924; Il1rak; interleukin 1 receptor associated kinase 1; interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase-1; IRAK; Irak1; IRAK-1; IRAK1-S; mPLK; pelle; Pelle homolog; pelle-like protein kinase; Plpk; RGD1563841

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16179, 3654

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with mouse based on sequence homology
  • Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways
  • It is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation
  • IRAK's association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation
  • Alternatively, IRAK1 can phosphorylate TIRAP to promote its ubiquitination and subsequent degradation
  • IRAK1 also phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus
  • This results in the transcriptional activiation of type I IFN genes, which drive the cell in an antiviral state.

Compare Similar Items

Show Difference

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Invitrogen

71-001-5

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Antigen:
IRAK1

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P51617, Q62406

Gene Symbols:
Irak1

Immunogen:
proprietary

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
19HCLC

Conjugate:
Unconjugated

Gene:
Irak1

Gene Alias:
AA408924; Il1rak; interleukin 1 receptor associated kinase 1; interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase-1; IRAK; Irak1; IRAK-1; IRAK1-S; mPLK; pelle; Pelle homolog; pelle-like protein kinase; Plpk; RGD1563841

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16179, 3654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Applied Biosystems™

71-002

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Antigen:
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Classification:
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Concentration:
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Formulation:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
__

Quantity:
5 mL

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Store in refrigerator (2°C to 8°C).

Form:
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Applied Biosystems™

71-003

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Antigen:
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Classification:
__

Concentration:
__

Formulation:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Quantity:
1 mL

Primary or Secondary:
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Target Species:
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Product Type:
Anti-E.coli O157 Bead

Isotype:
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Applications:
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Clone:
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Conjugate:
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Gene:
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Gene Alias:
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Host Species:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
Each unit of product contains 1 mL Dynabeads™ anti-E. coli O157.Store at 2°C to 8°C.

Form:
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Fischer Scientific

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Antigen:
__

Classification:
__

Concentration:
5 U/μL

Formulation:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Quantity:
100 U

Primary or Secondary:
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Target Species:
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Product Type:
DNA Polymerase

Isotype:
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Applications:
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Clone:
__

Conjugate:
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Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
__