71-201-1

Phospho-WWTR1 (Ser311) Recombinant Polyclonal Antibody (14HCLC), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 71-201-1-Each-of-1 In Stock ₹ 42,780.00

71-201-1 - Each of 1

₹ 42,780.00

In Stock

Quantity

1

Base Price: ₹ 42,780.00

GST (18%): ₹ 7,700.40

Total Price: ₹ 50,480.40

Antigen

Phospho-WWTR1 (Ser311)

Classification

Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

Q9GZV5

Gene Symbols

WWTR1

Immunogen

Peptide corresponding to human Phospho-WWTR1 (Ser311) [aa307-aa314]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry

Clone

14HCLC

Conjugate

Unconjugated

Gene

WWTR1

Gene Alias

2310058J06Rik; 2610021I22Rik; C78399; DKFZp586I1419; FLJ27004; FLJ45718; Tafazzin; TAZ; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

25937

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • This antibody is predicted to react with Monkey, Bovine, Cat, Sheep
  • Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • WW domain-containing transcription regulator protein 1 (WWTR1) is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor supression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1
  • In turn, MOB1 phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation
  • WWTR1 regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex
  • WWTR1 also regulates embryonic stem-cell self-renewal and promotes cell proliferation and epithelial-mesenchymal transition.

Compare Similar Items

Show Difference

Img

Invitrogen

71-201-1

--


Antigen:
Phospho-WWTR1 (Ser311)

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9GZV5

Gene Symbols:
WWTR1

Immunogen:
Peptide corresponding to human Phospho-WWTR1 (Ser311) [aa307-aa314]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Clone:
14HCLC

Conjugate:
Unconjugated

Gene:
WWTR1

Gene Alias:
2310058J06Rik; 2610021I22Rik; C78399; DKFZp586I1419; FLJ27004; FLJ45718; Tafazzin; TAZ; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25937

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

71-201-9

--


Antigen:
BOB-1

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q16633

Gene Symbols:
POU2AF1

Immunogen:
Protein corresponding to human BOB-1 [aa1-aa256]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Clone:
2HCLC

Conjugate:
Unconjugated

Gene:
POU2AF1

Gene Alias:
B-cell-specific coactivator OBF-1; BOB.1; Bob1; BOB-1; OBF.1; OBF1; Obf-1; OCAB; OCA-B; OCT-binding factor 1; POU class 2 associating factor 1; POU domain class 2-associating factor 1; POU domain, class 2, associating factor 1; Pou2af1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5450

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

71-202-3

--


Antigen:
ULBP3

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9BZM4

Gene Symbols:
ULBP3

Immunogen:
Protein corresponding to human ULBP3 [aa30-aa171]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Clone:
11HCLC

Conjugate:
Unconjugated

Gene:
ULBP3

Gene Alias:
ALCAN-gamma; N2DL3; N2DL-3; NKG2D ligand 3; NKG2D ligand3; NKG2DL3; RAET1N; Retinoic acid early transcript 1N; UL16 binding protein 3; UL16-binding protein 3; ULBP; ULBP 3; ULBP3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79465

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

71-204-3

--


Antigen:
JIK

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9H2K8

Gene Symbols:
TAOK3

Immunogen:
Protein corresponding to human JIK [aa322-aa432]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
1HCLC

Conjugate:
Unconjugated

Gene:
TAOK3

Gene Alias:
2900006A08Rik; A130052D22; A430105I05Rik; Arg357; Axotomy-related gene 357 protein; CTCL-associated antigen HD-CL-09; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; dendritic cell-derived protein kinase; DKFZp666H245; DPK; EC 2.7.11.1; FLJ31808; hKFC-A; JIK; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; KDS; Kinase from chicken homolog A; MAP3K18; Serine/threonine-protein kinase TAO3; STE20-like kinase; STE2-like kinase; tao; TAO kinase 3; Taok3; Thousand and one amino acid protein 3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51347

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid