71-215-0
TET2 Recombinant Polyclonal Antibody (7HCLC), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 71-215-0-Each-of-1 | In Stock | ₹ 41,068.80 |
71-215-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,068.80
GST (18%): ₹ 7,392.384
Total Price: ₹ 48,461.184
Antigen
TET2
Classification
Recombinant Polyclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
Q6N021
Gene Symbols
TET2
Immunogen
Protein corresponding to human TET2 [aa1700-aa2002]
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Immunocytochemistry
Clone
7HCLC
Conjugate
Unconjugated
Gene
TET2
Gene Alias
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
54790
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- This antibody is predicted to react with Monkey, Pig, Cat
- Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
- They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
- While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
- The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
- TET2 is a dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydromethylcytosine (5hmC) and plays a key role in active DNA demethylation
- TET2 has a preference for 5-hydroxymethylcytosine in CpG motifs
- It mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC) and conversion of 5fC to 5-carboyxlcytosine (5caC)
- Conversion of 5mC into 5hmC, 5fC, and 5caC probably constitutes the first step in cytonsine demethylation
- In addition to TET2’s role in DNA demethylation, it is also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT
- Mutations in the genes can result in Polycythemia vera and Myelodysplastic syndrome.
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Antigen: TET2
Classification: Recombinant Polyclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: Q6N021
Gene Symbols: TET2
Immunogen: Protein corresponding to human TET2 [aa1700-aa2002]
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Immunocytochemistry
Clone: 7HCLC
Conjugate: Unconjugated
Gene: TET2
Gene Alias: Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 54790
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TET2
Classification:
Recombinant Polyclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q6N021
Gene Symbols:
TET2
Immunogen:
Protein corresponding to human TET2 [aa1700-aa2002]
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Immunocytochemistry
Clone:
7HCLC
Conjugate:
Unconjugated
Gene:
TET2
Gene Alias:
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
54790
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Connexin 30
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: O95452, P70689
Gene Symbols: GJB6
Immunogen: A synthetic peptide derived from the unique C-terminus of the mouse Connexin 30 protein
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Feline, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: Z-PP9
Conjugate: Unconjugated
Gene: GJB6
Gene Alias: AA958971; connexin 30; connexin-30; CX30; Cxn-30; D14Bwg0506e; DFNA3; DFNA3B; DFNB1B; ECTD2; ectodermal dysplasia 2, hidrotic (Clouston syndrome); ED2; EDH; Gap junction beta-6 protein; gap junction membrane channel protein beta 6; gap junction protein beta 6; gap junction protein, beta 6; gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6, 30kDa; Gjb6; HED; HED2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 101082796, 10804, 14623, 84403
Content And Storage: -20°C
Form: Liquid
Antigen:
Connexin 30
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
O95452, P70689
Gene Symbols:
GJB6
Immunogen:
A synthetic peptide derived from the unique C-terminus of the mouse Connexin 30 protein
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Feline, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
Z-PP9
Conjugate:
Unconjugated
Gene:
GJB6
Gene Alias:
AA958971; connexin 30; connexin-30; CX30; Cxn-30; D14Bwg0506e; DFNA3; DFNA3B; DFNB1B; ECTD2; ectodermal dysplasia 2, hidrotic (Clouston syndrome); ED2; EDH; Gap junction beta-6 protein; gap junction membrane channel protein beta 6; gap junction protein beta 6; gap junction protein, beta 6; gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6, 30kDa; Gjb6; HED; HED2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
101082796, 10804, 14623, 84403
Content And Storage:
-20°C
Form:
Liquid
Antigen: __
Classification: __
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Immunogen: __
Quantity: 500 mg
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500 mg
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Quantity: 11 Reactions
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Content And Storage: ≤-70°C
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11 Reactions
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≤-70°C
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