71-275-2

LSD1 Recombinant Polyclonal Antibody (3HCLC), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 71-275-2-Each In Stock ₹ 36,846.41

71-275-2 - Each

₹ 36,846.41

In Stock

Quantity

1

Base Price: ₹ 36,846.41

GST (18%): ₹ 6,632.354

Total Price: ₹ 43,478.764

Antigen

LSD1

Classification

Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

O60341, Q6ZQ88

Gene Symbols

KDM1A

Immunogen

Protein corresponding to human LSD1 [aa500-aa852]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, Immunocytochemistry, Western Blot

Clone

3HCLC

Conjugate

Unconjugated

Gene

KDM1A

Gene Alias

1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23028, 99982

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • This antibody is predicted to react with Mouse, Rat, Bovine Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor
  • LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain
  • This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase
  • It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed
  • LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3
  • This protein may play a role in the repression of neuronal genes
  • Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity
  • It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes
  • Mutations affecting this gene can result in cleft palate, psychomotor retardation, and distintive facial features.

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Invitrogen

71-275-2

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Antigen:
LSD1

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O60341, Q6ZQ88

Gene Symbols:
KDM1A

Immunogen:
Protein corresponding to human LSD1 [aa500-aa852]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Clone:
3HCLC

Conjugate:
Unconjugated

Gene:
KDM1A

Gene Alias:
1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23028, 99982

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Invitrogen

71-279-1

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Antigen:
JMJD2B

Classification:
Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O94953

Gene Symbols:
KDM4B

Immunogen:
Protein corresponding to human JMJD2B [aa400-aa600]

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry

Clone:
4HCLC

Conjugate:
Unconjugated

Gene:
KDM4B

Gene Alias:
4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23030

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

MilliporeSigma™

71-279-3

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
500 g

Primary or Secondary:
__

Target Species:
__

Product Type:
Microbiology Media

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
15°C to 30°C

Form:
__

Img

MilliporeSigma™

71-280-3

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
500 g

Primary or Secondary:
__

Target Species:
__

Product Type:
Peptone

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
15°C to 30°C

Form:
__