7105465

ER alpha/NR3A1 Antibody (SPM567), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

ER alpha/NR3A1

Dilution

Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Accession No.

P03372

Gene ID (Entrez)

2099

Immunogen

Recombinant human Estrogen Receptor alpha protein (aa2-185)

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Molecular Weight of Antigen

67 kDa

Clone

SPM567

Applications

Western Blot, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Angiogenesis, Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Phospho Specific, Signal Transduction, Transcription Factors and Regulators

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1

Gene Symbols

ESR1

Isotype

IgG1 κ

Purification Method

Protein A purified

Test Specificity

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.

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Description

  • ER alpha/NR3A1 Monoclonal specifically detects ER alpha/NR3A1 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

7105465

Mouse Monoclonal Antibody...


Antigen:
ER alpha/NR3A1

Dilution:
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P03372

Gene ID (Entrez):
2099

Immunogen:
Recombinant human Estrogen Receptor alpha protein (aa2-185)

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
67 kDa

Clone:
SPM567

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Angiogenesis, Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Phospho Specific, Signal Transduction, Transcription Factors and Regulators

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1

Gene Symbols:
ESR1

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.

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7105467

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Antigen:
GM-CSF

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Primate

Gene Accession No.:
P04141

Gene ID (Entrez):
1437

Immunogen:
Recombinant human GM-CSF protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
22 kDa

Clone:
SPM469

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Rat

Research Discipline:
Cytokine Research, Immunology

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, GM-CSF, GMCSFgranulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony stimulating factor, MGC131935, MGC138897, molgramostin, sargramostim

Gene Symbols:
CSF2

Isotype:
IgG2a κ

Purification Method:
Protein A purified

Test Specificity:
Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.

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Antigen:
Chorionic Gonadotropin alpha Chain (HCG alpha)

Dilution:
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P01215

Gene ID (Entrez):
1081

Immunogen:
Recombinant hCG alpha protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
13 kDa

Clone:
HCGa/53

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
__

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CGA glycoprotein hormones, alpha polypeptide, CG-ALPHA, FSHA, GPHa, GPHA1, HCG, LHA, TSHA

Gene Symbols:
CGA

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
This MAb reacts with a protein of ∼13kDa, identified as alpha sub-unit of HCG. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH).

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7105468

Mouse Monoclonal Antibody...


Antigen:
Chorionic Gonadotropin alpha Chain (HCG alpha)

Dilution:
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P01215

Gene ID (Entrez):
1081

Immunogen:
Recombinant hCG alpha protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
13 kDa

Clone:
HCGa/53

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
__

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CGA glycoprotein hormones, alpha polypeptide, CG-ALPHA, FSHA, GPHa, GPHA1, HCG, LHA, TSHA

Gene Symbols:
CGA

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
This MAb reacts with a protein of ∼13kDa, identified as alpha sub-unit of HCG. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH).