Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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NF-H
1.0 mg/mL
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), CyTOF
Unconjugated
Mouse
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
PBS with No Preservative
4744
Triton-X 100 insoluble protein fraction of rat brain
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
200 kDa
SPM203
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry, Immunohistochemistry-Paraffin : 0.25 - 0.5 ug/ml, CyTOF-ready
Monoclonal
Purified
RUO
Human, Mouse, Rat, Porcine, Chicken
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
NEFH
IgG1
Protein A or G purified
This MAb reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.