7105855

ABO, Blood Group A Antigen Antibody (HE-193) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

ABO, Blood Group A Antigen

Concentration

1.0 mg/mL

Applications

Immunohistochemistry (Paraffin), Immunofluorescence, Agglutination

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Alias

A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT

Gene Symbols

ABO

Isotype

IgM κ

Purification Method

Protein A or G purified

Test Specificity

This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Clone

HE-193

Dilution

Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, Agglutination

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Formulation

PBS with No Preservative

Gene ID (Entrez)

28

Immunogen

Mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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Description

  • ABO, Blood Group A Antigen Monoclonal specifically detects ABO, Blood Group A Antigen in Human samples
  • It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, Agglutination.

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Mouse Monoclonal Antibody...


Antigen:
ABO, Blood Group A Antigen

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence, Agglutination

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Alias:
A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT

Gene Symbols:
ABO

Isotype:
IgM κ

Purification Method:
Protein A or G purified

Test Specificity:
This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Clone:
HE-193

Dilution:
Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, Agglutination

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with No Preservative

Gene ID (Entrez):
28

Immunogen:
Mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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Antigen:
ABO, Blood Group A Antigen

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence, Agglutination

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Alias:
A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT

Gene Symbols:
ABO

Isotype:
IgM κ

Purification Method:
Protein A or G purified

Test Specificity:
__

Clone:
HEB-20

Dilution:
Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, Agglutination

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with No Preservative

Gene ID (Entrez):
28

Immunogen:
Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva of secretors with blood group B

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Img

Fischer Scientific

7105856

Mouse Monoclonal Antibody...


Antigen:
ABO, Blood Group A Antigen

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence, Agglutination

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Alias:
A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT

Gene Symbols:
ABO

Isotype:
IgM κ

Purification Method:
Protein A or G purified

Test Specificity:
__

Clone:
HEB-20

Dilution:
Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, Agglutination

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with No Preservative

Gene ID (Entrez):
28

Immunogen:
Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva of secretors with blood group B

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Img

Fischer Scientific

7105857

Mouse Monoclonal Antibody...


Antigen:
ABO, Blood Group A Antigen

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence, Agglutination

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Alias:
A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT

Gene Symbols:
ABO

Isotype:
IgM κ

Purification Method:
Protein A or G purified

Test Specificity:
This MAb preferably reacts with determinants of chain A and H type 3(Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R), but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Clone:
HE-10

Dilution:
Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, Agglutination

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS with No Preservative

Gene ID (Entrez):
28

Immunogen:
Mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.