7106001

alpha-Fetoprotein/AFP Antibody (C2) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

alpha-Fetoprotein/AFP

Concentration

1.0 mg/mL

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Cancer, Cancer Stem Cells, GPCR, Stem Cell Markers, Tumor Biomarkers

Formulation

PBS with No Preservative

Gene ID (Entrez)

174

Immunogen

Alpha fetoprotein (AFP) purified from serum of a hepatoma patient.

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen

70 kDa

Clone

C2

Dilution

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 1 - 2 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Mouse, Bovine (Negative), Canine (Negative), Rat (Negative)

Gene Alias

Alpha-1-fetoprotein, Alpha-fetoglobulin, alpha-fetoprotein, FETA, HP, HPAFP

Gene Symbols

AFP

Isotype

IgG1 κ

Purification Method

Protein A or G purified

Test Specificity

It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Description

  • alpha-Fetoprotein/AFP Monoclonal specifically detects alpha-Fetoprotein/AFP in Human, Mouse, Bovine (Negative), Canine (Negative), Rat (Negative) samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

7106001

Mouse Monoclonal Antibody...


Antigen:
alpha-Fetoprotein/AFP

Concentration:
1.0 mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cancer Stem Cells, GPCR, Stem Cell Markers, Tumor Biomarkers

Formulation:
PBS with No Preservative

Gene ID (Entrez):
174

Immunogen:
Alpha fetoprotein (AFP) purified from serum of a hepatoma patient.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
70 kDa

Clone:
C2

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 1 - 2 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Bovine (Negative), Canine (Negative), Rat (Negative)

Gene Alias:
Alpha-1-fetoprotein, Alpha-fetoglobulin, alpha-fetoprotein, FETA, HP, HPAFP

Gene Symbols:
AFP

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Img

Fischer Scientific

7106002

Mouse Monoclonal Antibody...


Antigen:
Retinol Binding Protein RBP

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
__

Formulation:
PBS with No Preservative

Gene ID (Entrez):
5947

Immunogen:
Recombinant human retinol binding protein-1 (RBP1)

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
__

Clone:
RBP/872

Dilution:
Immunohistochemistry-Paraffin : 1 - 2 ug/ml, Immunofluorescence : 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Goat, Monkey, Rabbit

Gene Alias:
C, Cellular retinol-binding protein, CRABP-I, CRBP1CRBP-I, CRBPCellular retinol-binding protein I, CRBPI, RBPC, retinol binding protein 1, cellular, retinol-binding protein 1, retinol-binding protein 1, cellular

Gene Symbols:
RBP1

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.

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Fischer Scientific

7106003

Mouse Monoclonal Antibody...


Antigen:
Fibronectin

Concentration:
1.0 mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers

Formulation:
PBS with No Preservative

Gene ID (Entrez):
2335

Immunogen:
High molecular weight proteins secreted by cultivated human fibroblasts

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen:
__

Clone:
568

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 1 - 2 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
__

Gene Symbols:
FN1

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Epitope of this MAb is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ∼440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.

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Fischer Scientific

7106005

Rabbit Monoclonal Antibody...


Antigen:
His Tag

Concentration:
__

Applications:
Western Blot, ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Research Discipline:
__

Formulation:
PBS with 0.02% Proclin 300. with 0.02% Proclin 300

Gene ID (Entrez):
__

Immunogen:
Purified his tagged Fab fragment.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Molecular Weight of Antigen:
__

Clone:
3D5

Dilution:
Western Blot 1:100 - 1:2000, ELISA 1:100 - 1:2000

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Non-species specific

Gene Alias:
6 His epitope tag, 6X His, 6X-His, H, HHHHHH epitope tag, HHHHHH tag, HIS, His tag, Poly-histidine

Gene Symbols:
__

Isotype:
IgG

Purification Method:
Protein A or G purified

Test Specificity:
Carboxy-terminal oligo-histidine tags (6x His tags) of fusion proteins.