7143928
Phospho-KAP-1 (Ser824) Recombinant Rabbit Monoclonal Antibody (BL-246-7B5), Bethyl Laboratories
Rabbit Recombit Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Phospho-KAP-1 (Ser824)
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q13263
Gene ID (Entrez)
10155
Immunogen
Surrounding serine 824
Primary or Secondary
Primary
Content And Storage
4° C
Gene
TRIM28
Clone
BL-246-7B5
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias
Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p
Gene Symbols
TRIM28
Isotype
IgG
Purification Method
Purified
Product Type
Antibody
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For ICC, formaldehyde fixation is recommended
- Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells
- For IHC, epitope retrieval with c The KRAB (Kruppel-associated box) domain is about 45 amino acids in length and is a transcriptional repression domain found in numerous transcription factors
- There have been identified over 220 KRAB-zinc finger protein (KRAB-ZFP) genes in the human genome
- These proteins functionally repress transcription via specific interactions with KAP-1 (KRAB-associated protein 1)
- KAP-1 is an 835 amino acid polypeptide that contains a RING finger, B boxes, and a PHD finger
- KAP-1 has been shown to form complexes with KRAB-domain transcription factors and increase the efficiency with which they mediate repression
- KAP-1 has also been shown to directly interact with HP1 (heterochromatin protein 1) and KRAZ1 (Kruppel-associated box-containing zinc finger protein 1)
- KAP-1 directly targets KRAZ1 to the foci of centromeric heterochromatin containing HP1alpha, thus helping to regulate transcriptional repression
- Studies have shown that KAP-1 mutants with the ability to bind KRAB but unable to bind HP1 leads to random distribution of KRAZ1 and strong transcriptional activation.
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Antigen: Phospho-KAP-1 (Ser824)
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q13263
Gene ID (Entrez): 10155
Immunogen: Surrounding serine 824
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: TRIM28
Clone: BL-246-7B5
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias: Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p
Gene Symbols: TRIM28
Isotype: IgG
Purification Method: Purified
Product Type: Antibody
Antigen:
Phospho-KAP-1 (Ser824)
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q13263
Gene ID (Entrez):
10155
Immunogen:
Surrounding serine 824
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
TRIM28
Clone:
BL-246-7B5
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias:
Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p
Gene Symbols:
TRIM28
Isotype:
IgG
Purification Method:
Purified
Product Type:
Antibody
Antigen: CD3E
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P07766
Gene ID (Entrez): 916
Immunogen: Between 157 and 207
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: CD3E
Clone: BL-298-5D12
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias: FLJ18683; T3E; TCRE; CD3-epsilon; CD3e antigen; epsilon polypeptide TiT3 complex; T-cell antigen receptor complex; epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; HCD3
Gene Symbols: CD3E
Isotype: IgG
Purification Method: Purified
Product Type: Antibody
Antigen:
CD3E
Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P07766
Gene ID (Entrez):
916
Immunogen:
Between 157 and 207
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
CD3E
Clone:
BL-298-5D12
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias:
FLJ18683; T3E; TCRE; CD3-epsilon; CD3e antigen; epsilon polypeptide TiT3 complex; T-cell antigen receptor complex; epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; HCD3
Gene Symbols:
CD3E
Isotype:
IgG
Purification Method:
Purified
Product Type:
Antibody
Antigen: CD247/CD3Z
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P20963
Gene ID (Entrez): 919
Immunogen: Between 114 and 164
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: CD247
Clone: BL-336-1B2
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias: T3Z, CD3H, CD3Q, TCRZ, CD3-ZETA
Gene Symbols: CD247
Isotype: IgG
Purification Method: Purified
Product Type: Antibody
Antigen:
CD247/CD3Z
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P20963
Gene ID (Entrez):
919
Immunogen:
Between 114 and 164
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
CD247
Clone:
BL-336-1B2
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias:
T3Z, CD3H, CD3Q, TCRZ, CD3-ZETA
Gene Symbols:
CD247
Isotype:
IgG
Purification Method:
Purified
Product Type:
Antibody
Antigen: SMC1
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: Q14683, Q9CU62
Gene ID (Entrez): 24061, 8243
Immunogen: Between 1175 and C-term
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: SMC1A
Clone: BL-205-2G8
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias: RP6-29D12.1, CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Gene Symbols: __
Isotype: IgG
Purification Method: Purified
Product Type: Antibody
Antigen:
SMC1
Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
Q14683, Q9CU62
Gene ID (Entrez):
24061, 8243
Immunogen:
Between 1175 and C-term
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
SMC1A
Clone:
BL-205-2G8
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Alias:
RP6-29D12.1, CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Gene Symbols:
__
Isotype:
IgG
Purification Method:
Purified
Product Type:
Antibody