7143936

Ki-67 Recombinant Rabbit Monoclonal Antibody (BLR021E), Bethyl Laboratories

Rabbit Recombit Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Ki-67

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P46013

Gene ID (Entrez)

4288

Immunogen

Between 1200 and 1250

Primary or Secondary

Primary

Content And Storage

4° C

Gene

MKI67

Clone

BLR021E

Classification

Recombinant Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Alias

antigen identified by monoclonal antibody Ki-67, KIA, MIB-, MIB-1, PPP1R105, proliferation-related Ki-67 antigen, protein phosphatase 1, regulatory subunit 105

Gene Symbols

MKI67

Isotype

IgG

Purification Method

Ion-exchange chromatography

Product Type

Antibody

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections
  • For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases
  • The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus
  • Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase
  • Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis
  • Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms
  • In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index
  • The correlation between low Ki-67 index and histologically low-grade tumors is strong
  • Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.

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Antigen:
Ki-67

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P46013

Gene ID (Entrez):
4288

Immunogen:
Between 1200 and 1250

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MKI67

Clone:
BLR021E

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Alias:
antigen identified by monoclonal antibody Ki-67, KIA, MIB-, MIB-1, PPP1R105, proliferation-related Ki-67 antigen, protein phosphatase 1, regulatory subunit 105

Gene Symbols:
MKI67

Isotype:
IgG

Purification Method:
Ion-exchange chromatography

Product Type:
Antibody

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7143937

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Antigen:
Granzyme B

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P10144

Gene ID (Entrez):
3002

Immunogen:
Recombit protein representing Human Granzyme B

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
GZMB

Clone:
BLR022E

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Alias:
GrB

Gene Symbols:
GZMB

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

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Antigen:
FUS

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P35637, P56959

Gene ID (Entrez):
233908, 2521

Immunogen:
Between 1 and 50

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
FUS

Clone:
BLR023E

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Alias:
ALS6, FUS1, HNRNPP2, POMP75, TLS, 75 kDa DNA-pairing protein, RNA-binding protein FUS, fus-like protein, fusion gene in myxoid liposarcoma, heterogeneous nuclear ribonucleoprotein P2, oncogene FUS, oncogene TLS, translocated in liposarcoma protein

Gene Symbols:
__

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

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Antigen:
B7-H3/CD276

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q5ZPR3

Gene ID (Entrez):
80381

Immunogen:
between 484 to 534

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
CD276

Clone:
BLR025F

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
BBS with 0.09% sodium azide; pH 8.2

Gene Alias:
PSEC0249; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2; B7 homolog 3; CD276 antigen; costimulatory molecule; HB7H3

Gene Symbols:
CD276

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody