7144059
BHC110/LSD1 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
BHC110/LSD1
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
AOF2, LSD1
Gene Symbols
KDM1A
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O60341
Gene ID (Entrez)
23028
Immunogen
Between 50 and 100
Primary or Secondary
Primary
Content And Storage
4° C
Gene
KDM1A
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan and Gorilla LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor
- LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain
- This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase
- It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed
- LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3
- This protein may play a role in the repression of neuronal genes
- Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity
- It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes
- Mutations affecting this gene can result in cleft palate, psychomotor retardation, and distintive facial features.
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Antigen: BHC110/LSD1
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: AOF2, LSD1
Gene Symbols: KDM1A
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O60341
Gene ID (Entrez): 23028
Immunogen: Between 50 and 100
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: KDM1A
Antigen:
BHC110/LSD1
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
AOF2, LSD1
Gene Symbols:
KDM1A
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O60341
Gene ID (Entrez):
23028
Immunogen:
Between 50 and 100
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
KDM1A
Antigen: Bub3
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: BUB3 budding uninhibited by benzimidazoles 3 homolog; OTTHUMP00000020682; budding uninhibited by benomyl; mitotic checkpoint component; mitotic checkpoint protein BUB3
Gene Symbols: BUB3
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O43684
Gene ID (Entrez): 9184
Immunogen: Between 275 and 325
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: BUB3
Antigen:
Bub3
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
BUB3 budding uninhibited by benzimidazoles 3 homolog; OTTHUMP00000020682; budding uninhibited by benomyl; mitotic checkpoint component; mitotic checkpoint protein BUB3
Gene Symbols:
BUB3
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O43684
Gene ID (Entrez):
9184
Immunogen:
Between 275 and 325
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
BUB3
Antigen: AF9
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: AF-9 protein
Gene Symbols: MLLT3
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P42568
Gene ID (Entrez): 4300
Immunogen: Between 250 and 300
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: MLLT3
Antigen:
AF9
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
AF-9 protein
Gene Symbols:
MLLT3
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P42568
Gene ID (Entrez):
4300
Immunogen:
Between 250 and 300
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
MLLT3
Antigen: 4E-T/eIF4E-T
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: EIF4ENIF1; 4E-T; Clast4; FLJ21601; 2610509L04Rik; eukaryotic translation initiation factor 4E nuclear import factor 1; eIF4E-transporter; FLJ26551; OTTHUMP00000063276
Gene Symbols: EIF4ENIF1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9NRA8
Gene ID (Entrez): 56478
Immunogen: Between 925 and C-term
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: EIF4ENIF1
Antigen:
4E-T/eIF4E-T
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
EIF4ENIF1; 4E-T; Clast4; FLJ21601; 2610509L04Rik; eukaryotic translation initiation factor 4E nuclear import factor 1; eIF4E-transporter; FLJ26551; OTTHUMP00000063276
Gene Symbols:
EIF4ENIF1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9NRA8
Gene ID (Entrez):
56478
Immunogen:
Between 925 and C-term
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
EIF4ENIF1